李张曼玉,李晓盼,于莹,王超

• 1:承德医学院
• 2:保定市第一中心医院CCU

摘要(Abstract)：

目的探讨血浆致动脉硬化指数(AIP)水平与冠状动脉病变严重程度的相关性。方法纳入2017年1月至2017年12月因胸痛、心前区不适在保定市第一中心医院住院,拟诊为冠心病并行冠状动脉造影(CAG)的患者共183例。其中经CAG确诊为冠心病的患者共144例,根据SYNTAX评分,分为低分组(1～22分)57例、中分组(23～32分)34例、高分组(>33分)53例;其余经CAG证实无冠心病的39例患者为对照组。测定各组血脂水平并计算AIP。采用Spearman分析AIP与SYNTAX评分的相关性。结果四组患者年龄、性别、糖尿病发生率、吸烟史、饮酒史、体重指数比较,差异均无统计学意义(均P>0.05)。冠心病三组患者高血压病发生率、三酰甘油、AIP水平均高于对照组,而高密度脂蛋白胆固醇低于对照组,差异均有统计学意义(均P<0.05)。在低分组、中分组、高分组中,随着冠状动脉病变严重程度增加,三酰甘油以及AIP水平逐渐升高,高密度脂蛋白胆固醇水平逐渐降低(均P<0.05)。Spearman相关分析显示,AIP与SYNTAX评分呈正相关(r=0.422,P<0.001)。结论 AIP与冠状动脉病变严重程度存在相关性,AIP对预测冠状动脉病变及其病情进展有一定临床意义。

关键词(KeyWords)： 冠心病;血浆致动脉硬化指数;SYNTAX评分

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 李张曼玉,李晓盼,于莹,王超

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