P波振幅预测阵发性心房颤动肺静脉隔离射频消融术后复发的临床价值Clinical value of P wave amplitude in predicting postoperative recurrence of pulmonary vein isolation in patients with paroxysmal atrial fibrillation
王学忠,王岳松,汪韶君,樊琴,邵旭武,董学斌,方永华
摘要(Abstract):
目的评价阵发性心房颤动(房颤)肺静脉隔离射频消融患者术前P波振幅与术后复发之间的关系。方法回顾性分析接受肺静脉隔离射频消融治疗阵发性房颤患者的临床特征,测量相关导联P波的时限和振幅。术后随访3个月以上,按照术后复发与否分为复发组与未复发组,评估P波振幅在预测房颤术后复发中的价值。结果在50例患者中术后共13例复发房颤,其中2例再次射频消融成功,总射频消融成功率78.0%(39/50)。复发组患者年龄[(67.75±6.48)岁比(60.82±8.87)岁,P=0.007]、CHA_2DS_2-VASC评分[(2.21±1.25)分比(1.33±1.15)分,P=0.021]和左心房内径[(40.4±4.7)mm比(37.2±4.2)mm,P=0.028]均显著高于未复发组,差异均有统计学意义。复发组患者Ⅰ导联P波振幅[(0.065±0.038)m V比(0.095±0.038)m V,P=0.024]显著低于未复发组。Ⅰ导联P波振幅<0.1 m V在预测阵发性房颤肺静脉隔离射频消融术后复发的敏感度为79%,特异度为71%。多元回归分析显示,Ⅰ导联P波振幅<0.1 m V为房颤术后复发的独立危险因素(OR 2.36,95%CI 1.96~4.87,P=0.012)。结论Ⅰ导联P波低振幅可能是预测阵发性房颤肺静脉隔离射频消融术后复发的有效指标。
关键词(KeyWords): P波振幅;阵发性心房颤动;肺静脉隔离;复发
基金项目(Foundation):
作者(Author): 王学忠,王岳松,汪韶君,樊琴,邵旭武,董学斌,方永华
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