白细胞计数对不稳定型心绞痛患者不良心脑血管事件的预测价值Predictive value of leukocyte count for cardiovascular events in patients with unstable Angina pectoris
祖凌云,张庆华,高炜,郭丽君
摘要(Abstract)：
目的探讨白细胞计数水平及其分类对不稳定型心绞痛患者主要不良心脑血管事件的预测价值。方法对2000年12月至2003年1月入院的141例经临床和冠状动脉造影检查证实的冠心病不稳定型心绞痛患者常规测定白细胞水平及分类,随访46.2±6.6个月,以是否发生不良心脑血管事件将患者分为两组(事件组63例和无事件组78例),评价白细胞水平与主要不良心脑血管事件及其他临床指标的相关性。结果随访中共发生非致死性心血管事件55例,死亡8例。在调整了糖尿病、吸烟、高血压、高血脂、家族史、纤维蛋白原、尿酸及既往心肌梗死史等因素的影响后,白细胞计数水平与主要不良心脑血管事件的发生正相关,相对危险度为1.31,95%可信区间(CI)为1.15~1.49。事件组的单核细胞计数略高于无事件组,其差异具有统计学意义[(2.3±2.5)×109比(1.3±1.5)×109,P<0.05]。结论白细胞计数,尤其是单核细胞计数,可作为不稳定型心绞痛患者主要不良心脑血管事件重要的独立预测因子。
关键词(KeyWords)： 心绞痛;白细胞;单核细胞;预后
基金项目(Foundation):
作者(Author): 祖凌云,张庆华,高炜,郭丽君
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