胡昊,吴佳纬,李丹,余晓凡,李龙伟,余东彪,孔祥勇,华锦胜,周俊岭,陈鸿武,冯克福,余华,马礼坤

• 1:中国科学技术大学附属第一医院(安徽省立医院)心内科

摘要(Abstract)：

目的探讨主动脉内球囊反搏(IABP)在急性心肌梗死(AMI)合并心原性休克(CS)患者中的疗效及影响死亡率的危险因素。方法连续纳入2014年1月至2017年12月中国科技大学附属第一医院因AMI合并CS急诊置入IABP并行经皮冠状动脉介入治疗(PCI)的患者291例。根据住院期间是否死亡分为死亡组63例(21.6%)和存活组228例(78.4%),分析两组患者临床资料、实验室检查结果及术中并发症等。结果死亡患者年龄[(75.3±11.6)岁比(67.5±12.2)岁,P<0.001],糖尿病(63.5%比34.6%,P<0.001)、既往PCI史(4.8%比0.4%,P=0.033)、心房颤动(11.1%比0.9%,P<0.001)、左心室射血分数(LVEF)≤40%(74.6%比19.7%,P<0.001)、左主干病变(15.9%比1.3%,P<0.001)、血小板减少(4.8%比0.9%,P=0.017)比例及首次医疗接触至球囊扩张(FMC-to-B)时间[(11.18±3.63)h比(4.74±1.91)h,P<0.001]均显著高于存活组,差异均有统计学意义。logistic多因素回归分析发现,FMC-to-B时间(OR 2.291,95%CI 1.712～3.067,P<0.001)、LVEF(OR 0.909,95%CI 0.854～0.967,P=0.003)和PCI术后靶血管心肌梗死溶栓治疗试验(TIMI)血流分级≤Ⅱ级(OR28.329,95%CI 6.752～118.864,P<0.001)为死亡率的独立影响因素。结论 IABP是对AMI合并CS患者目前最常用的机械循环辅助救治手段,PCI术后靶血管TIMI血流分级≤Ⅱ级、LVEF以及FMC-to-B时间是预测患者死亡率的独立影响因素。

关键词(KeyWords)： 主动脉内球囊反搏;急性心肌梗死;心原性休克;药物支架置入

Abstract:

Keywords:

基金项目(Foundation): 安徽省公益性技术应用研究联动计划(15011d04032);; 安徽省科技攻关计划(1604a0802074)

作者(Author): 胡昊,吴佳纬,李丹,余晓凡,李龙伟,余东彪,孔祥勇,华锦胜,周俊岭,陈鸿武,冯克福,余华,马礼坤

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