经皮冠状动脉介入治疗并发冠状动脉穿孔临床特点和处理Incidence,management,and outcomes of coronary artery perforation: a single center experience
周国伟,张国兵,李为真,王毅,徐浩,储光,杨文艺,张治,温沁竹,孙宝贵,刘少稳
摘要(Abstract):
目的探讨经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术中并发冠状动脉穿孔(coronary artery perforation,CAP)的原因、临床表现、处理策略和院内转归。方法对上海交通大学附属第一人民医院2003年1月至2007年12月发生CAP的病例资料进行回顾性分析。结果 3312例PCI患者中有26例(0.8%)患者共发生27处CAP,其中指引导管引起的穿孔2例,导丝导致的穿孔15例(16处),支架术后的穿孔9例。16处导丝导致的CAP中,慢性完全闭塞病变12处,急性或近期闭塞病变3处,非闭塞病变1处。导丝导致的4例心脏压塞均为迟发性,最长者距离手术结束时间为46 h。9例支架术后的穿孔中,4例发生心脏压塞。本组资料共有9例发生心脏压塞,均进行心包穿刺引流,6例内科保守治疗治愈,3例行外科急诊修补术并冠状动脉旁路移植术,其中2例术后死亡。结论 CAP是PCI少见的并发症,导丝引起的CAP可导致迟发性心脏压塞甚至死亡。支架术后穿孔绝大部分在PCI术中即可发现,置入覆膜支架可能为首选措施。及时发现和正确处理是降低CAP死亡率的关键。
关键词(KeyWords): 经皮冠状动脉介入治疗;冠状动脉穿孔;心脏压塞
基金项目(Foundation):
作者(Author): 周国伟,张国兵,李为真,王毅,徐浩,储光,杨文艺,张治,温沁竹,孙宝贵,刘少稳
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