BACTERIAL ENDOCARDITIS:NATURAL HISTORY AND VALVULAR INVOLVEMENTBACTERIAL ENDOCARDITIS:NATURAL HISTORY AND VALVULAR INVOLVEMENT
Nguyen Quoc Thai,Do Doan Loi,Nguyen Lan Viet,Nguyen Ngoc Tuoc,Pham Gia Khai
摘要(Abstract)：
<正> A total of 92 patients with baetenal endocarditis (BE) were treatedduring 1/1995-5/1998.48 patients were intravenous drug addicts (ID)(52.2%).The averase age of ID patients was 30.48+/-6.06 years.Themajority had been using drugs for more than 6 months (79.3%).Thevegetations were located mainly in the left heart (90.9%).All the casesof BE in ID patients occured in native valves.Differences were foundbetween non-ID (NID) and ID with regard to heart failure in ID (62.5%versus 16%) and to cerebral vascular accidents (25% versus 13%).Positive blood cultures were significantly more frequent in ID (95.5%)versus NID (44.4%).Streptoccocal D infections were predominant in ID(56.8%) and Streptococcal alpha infections in NID patients (44.4%),thedifference being statistically significant.The hospital mortality rate wassimilar in both groups,18.7% and 18.2% in ID and NID patientsrespectively.There were no surgical interventions in the ID group.Conclusions:In an area with high prevalence of rheumatic valvular diseasethe incidence of bacterial endocarditis in ID and NID showed difference inpresentations.Even there were no surgery in the ID group,the short termmortality was similar.There is a need to investigate the clinical benefit ofvalvular replacement end the survival of the ID and NID patients,in an areawhere resources are limited.
关键词(KeyWords)：
基金项目(Foundation):
作者(Author): Nguyen Quoc Thai,Do Doan Loi,Nguyen Lan Viet,Nguyen Ngoc Tuoc,Pham Gia Khai