整合血管内超声和血流储备分数指导左主干分叉病变单支架“骑跨”技术的研究Integrated intravascular ultrasound and fractional flow reserve to guide single-stent crossover technique for left main and bifurcation lesions
刘健,王昭,王伟民,杨柳,刘传芬,李琪,马玉良,卢明瑜,赵红
摘要(Abstract):
目的采用单支架"骑跨"术治疗左主干分叉病变,观察术前左回旋支开口最小管腔面积(MLA)和斑块负荷(PB)与其术后发生心肌缺血的相关性研究。方法对5例左主干分叉病变患者进行术前血管内超声(IVUS)检查,单支架"骑跨"术后行血流储备分数(FFR)检查,评价术前左回旋支开口MLA和PB与术后存在心肌缺血的关系。结果 5例患者术前左主干平均MLA为(4.99±2.3)mm2,平均最小管腔直径(MLD)为(2.26±2.8)mm;左前降支开口及近端平均MLA为(4.01±2.0)mm2,平均PB为(68.15±10.1)%;左回旋支开口平均MLA为(4.94±0.4)mm2,平均PB为(66.00±6.0)%。对5例患者采用从左主干至前降支的单支架"骑跨"技术进行治疗后,仅1例(病例2)患者左回旋支的FFR为0.42,行双支架术治疗后,左回旋支的FFR升至0.84;其余4例患者左回旋支的FFR均大于0.75。结论整合血管内超声和血流储备分数技术,有可能获得左回旋支开口预测单支架术后发生心肌缺血的临界值。
关键词(KeyWords): 血管内超声;血流储备分数;分叉病变;单支架骑跨;最小管腔面积
基金项目(Foundation): 北京大学人民医院院内基金(RDC2013-20)
作者(Author): 刘健,王昭,王伟民,杨柳,刘传芬,李琪,马玉良,卢明瑜,赵红
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