Ras基因及P21蛋白与心血管疾病
周玉杰,汪丽蕙,邓洁焰
摘要(Abstract)：
关键词(KeyWords)：
基金项目(Foundation):
作者(Author): 周玉杰,汪丽蕙,邓洁焰
参考文献(References)：
- 1 Barbacid M. ras genes. Ann Rev Biochem, 1987, 56: 779.
- 2 Cheng R l Bradford S, Barnes D, et al. Cloning, sequencing,and embryonic expression of an N-ras proto-oncogene isolated from an enriched zebrafish cDNA library. Mol Mar Bol Biotechnol, 1997, 6: 40-7.
- 3 Capon DJ. Complete nucleotide sequences of the T 24 human bladder carcinoma oncogene and its normal homologue.Nature, 1983, 302: 307-341.
- 4 McGrath JP. Structure and organization of the hurnan K-rasproto-oncogene and a related processed psceudogene. Nature, 1985, 304: 501-504.
- 5 Shimizld K. Structure of K-ras gene of human lung carcincrma cell line Calu-1. Nature, 1983, 304: 497-501.
- 6 Shih TY. Identification of a sarcoma virus-codeled phosphoprotein in nonproducer cens trans formed by kirstenor Harrey marine sarcoma virus. Virobey, 1979,96: 64-68.
- 7 Burgoyne RD. Small GTP-binding proteins. Trends in Biological Science, 1989, 14: 394-395.
- 8 Bar-Sagi D. Induction of membrane ruffing and fluid-phasepinocytosis in quiescent fibrobIasts by ras proteins. Science,1986, 233: 1061- 1068.
- 9 Jun Carlos L. Rapid stimulation of diacylglycerol productionin Xenopus beytes by microinjection of H-ras P21. Science,1987, 233: 533-536.
- 10 Trahey M. A cytoplasmic protein stimulates normal N-rasP21 GTP ase, but dose not affects oncogenic mutants. Science, 1987, 238: 542-545.
- 11 Ramocki MB, Johnson SE, White MA, et al. Signalingthrough mitogen-activated protein kinase and Rac/Rho doesnot duplicate the effects of activated Ras on skeletal myogenesis. Mol Cell Biol, 1997, 17: 3547-55.
- 12 Smith MA, Fanger GR,O Connor LT, et al. Selective regulation of agrin mRNA induction and ahernative splicing inPC12 cells by Ras-dependent actions of nerve growth factor. J Bol Chem, 1997, 272: 15675-81.
- 13 Levy P, Munier A, Baron Defage S,et al. L'activation oncogenique de P2l ras ou pp60c-src dans les cellules coliqueshumaines Caco-2 induit des alterations post-traductionnellesdu syndecan- 1. Bull-Cancer, 1997, 84: 235-7.
- 14 Gomyo Y,Ikeda M,Osaki M, et al. Expression of P21 (wafl/cipl/sdil), but not P53 protein, is a factor in the survival ofpatients with advanced gastric carcinotna. Cancer, 1997, 79:2067-72.
- 15 Nishiya T, Uehara T, Edamatsu H, et al. Activation of Statland subSequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is indePendent of interferongamma-induced MAPK activation that is mediated by P21
- 16 Scambia G, Masciullo V, Benedetti PP. Prognostic significance of ras/P21 alterations in human ovarian cancer. Br JCancer, 1997, 75: 1547-53.
- 17 Riley J, Mandel HG,Sinha S,et al. In vitro activation of thehuman Harvey-ras proto-oncogene by aflatoxin B1- Carcinogenesis, 1997 , 18: 905- 10.
- 18 Ueno H, Yamamoto H, Ito S, et al. Adenovirus-mediatedtransfer of a dominant-negative H-ras suppresses neolntimalformation in balloon-injured arteries in vivo. ArteriosclerThromb-Vasc Bol, 1997: 17: 898-904.
- 19 cosgaya JM, Recio JA, Aranda A. Innuence of Ras andretinoic acid on nerve growth factor induction of transingene expression in PC12 cells. Onogene, 1997, 14: 1687-96.
- 20 de Vries JE,Ten KJ,Bosman FT. P21 ras in carcinogenesis.Pathol-Res-Pract, 1996, 192: 6 58. 68.
- 21 Kovacic MB,Zlock DW,Gardner DG. Ras inhibits Jun-activated human atrial natriuretic peptide gene transcription incultured ventriculer myocytes. Circ Res, 1997, 80: 580-8.