外科瓣膜置换术后瓣周漏相关性溶血的机制探讨及介入治疗进展Mechanism of paravalvular leak hemolysis after surgical valve replacement and progress of interventional therapy
邢超凡,潘欣,何奔
摘要(Abstract):
人工瓣膜置换术后瓣周漏(PVL)是外科瓣膜置换术后较常见的并发症之一,临床表现为心功能不全和(或)溶血。相较而言,溶血多发生在机械金属瓣置换术后,发生率相对较低且易被忽视和误诊。经导管PVL封堵术是外科手术高危患者的替代手段,可改善心力衰竭症状、降低死亡率,但该方法对溶血的临床研究较少,且术后可发生封堵器诱发的溶血加重。本文就外科瓣膜置换术后PVL相关性溶血的机制和介入治疗进展予以系统综述。
关键词(KeyWords): 瓣周漏;溶血;瓣膜置换术;介入
基金项目(Foundation): 上海市科委科研计划项目(17411970900)
作者(Author): 邢超凡,潘欣,何奔
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