冠心病合并2型糖尿病与非糖尿病患者的冠状动脉造影配对分析Comparisons of angiographic characteristics of coronary artery between patients with noninsulin dependent diabetes and matched nondiabetes
胡雪松,虞准,方卫华,衣为民
摘要(Abstract):
目的 了解 2型糖尿病患者冠状动脉病变的造影特点。方法 对 4 5例有 2型糖尿病合并冠心病患者的冠状动脉造影结果进行分析 ,并与配对的 4 5例无糖尿病患者冠状动脉病变进行比较。结果 两组间病变血管数量差异无显著性 ;两组间“罪犯”病变狭窄程度差异无显著性 ;两组间非闭塞性“罪犯”病变的形态方面差异无显著性 ;两组间“罪犯”血管病变类型比较均差异无显著性。结论 2型糖尿病患者与非糖尿病患者在冠状动脉病变的严重性和范围等方面无明显差异。
关键词(KeyWords): 糖尿病;冠状动脉造影;冠状动脉病变
基金项目(Foundation):
作者(Author): 胡雪松,虞准,方卫华,衣为民
参考文献(References):
- 1HambyRL ,ShermanL ,MehtaL ,etal.Reappraisaloftheroleofthediabeticstateincoronaryarterydisease.Chest,1976,70:251257.
- 2RobertsonWB ,StrongJP .Arteriosclerosisinpersonswithhypertensionanddiabetesmellitus.LabInvest,1968,19:528551.
- 3PajunenP ,MarkkuS ,Vieminen,etal.Quantitiescomparisonofangiographiccharacteristicsofcoronaryarterydiseaseinpatientswithnoninsulindependentdiabetesmellituscomparedwithmatchednondiabeticcontrolsubjects.AmJCardiol,1997,80:550556.
- 4VliestraRE ,KronmalRA ,FryeRL ,etal.FactorsaffectingtheextentandseverityofcoronaryarteryinpatientsenrolledintheCoronaryArterySurgeryStudy.Arteriosclerosis,1982,2:208215.
- 5WallerBF ,PalumboPJ,LieLT ,etal.Statusofthecoronaryarteriesatnecropsyindiabetesmellituswithonsetafterage30years.Analysisof229diabeticpatientswithandwithoutclinicalevidenceofcoronarydiseaseandcomparisonto183controlsubjects.AmJMed,1980,69:498506.
- 6DiabetesArteriosclerosisInterventionStudy.Effectoffenofibrateonprogressionofcoronary arterydiseaseintype2diabetes:theDiabetesAthrosclrosisInterventionStudy,arandomizedstudy.TheLANCET ,2001,359:905910.
- 7AmbroseJA ,LsraeIDH .Angiographyinunstableangina.AmJCardiol,1991,68:7879.
- 8刘文斓,张金荣,吕树铮.糖尿病合并冠心病患者的冠状动脉造影分析.中国糖尿病杂志,1999,7:2224.
- 9VigoritaVJ,MooreGW ,HuichinsGM .Absenceofcorrelationbetweencoronaryarteryarteriosclerosisandseverityordurationofdiabetesmellitusofadultonset.AmJCardiol,1980,46:535542.
- 10DortimerAC ,ShenoyPN ,ShiroffRA .Diffusecoronarydiseaseindiabeticpatients:faceorfiction?Circulation,1978,57:133136.
- 11JarrettRJ.Riskfactorsforcoronaryheartdiseaseindiabeticmellitus.Diabetes,1992,41(Supply2):24.
- 12AntoioM ,GottoJR .Triglyceride aforgottenriskfactor.Circulation,1998,97:10271028.
- 13ArchboldRA ,TimmisAD .Modificationofcoronaryarterydiseaseprogressionbycholesterol loweringtherapy:theangiographicstudies.CurrOpinLipidol,1999,10:527534.
- 14陈明,高炜,朱国英,等.冠心病合并非胰岛素依赖型糖尿病患者冠状动脉造影特点.中华内科杂志,1998,38:2729.
- 15MarkkuLK .Hyperglycemiaandcardiovasculardiseaseintype2diabetes.Diabetes,1999,48:937940.
- 16UKProspectiveDiabetesStudyGroup.Intensiveblood glucosecontrolwithsulphonylureaseorinsulincomparedwithconventionaltreatmentandriskofcomplicationinpatientswithtype2diabetes.Lancet,1998,352:837853.