高涵翔,白明,赵存瑞,赵晶,潘晨亮,张钲

• 1:兰州大学第一医院心血管内科

摘要(Abstract)：

目的观察重症急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)围术期给予持续肾替代治疗(CRRT)的安全性和有效性。方法纳入2016年1月至2017年12月在兰州大学第一医院监护中心冠心病重症监护室(CCU)住院的AMI患者945例,进行回顾性分析,并筛选出其中PCI围术期行CRRT患者21例,分析比较AMI患者的基线资料特点,评价CRRT治疗前后心功能、肾功能、肝功能等指标的变化趋势。结果 CRRT治疗后24 h、48 h患者心率比CRRT治疗前有所下降,差异有统计学意义(P=0.038),患者平均收缩压、舒张压与CRRT治疗前比较虽均有轻微下降,但差异均无统计学意义(均P>0.05)。CRRT治疗后心功能KillipⅠ~Ⅱ级(57.1%,12/21)比CRRT治疗前(23.8%,5/21)有明显改善,差异有统计学意义(P=0.001)。CRRT治疗后24 h、48 h尿素氮、肌酸酐、谷草转氨酶、谷丙转氨酶及总胆红素均较CRRT前好转,差异均有统计学意义(P<0.05)。结论重症AMI患者在PCI围术期给予CRRT治疗是安全有效的。

关键词(KeyWords)： 急性心肌梗死;经皮冠状动脉介入治疗;持续肾替代治疗

Abstract:

Keywords:

基金项目(Foundation): 甘肃省兰州市城关区科技计划项目(2016-7-15)

作者(Author): 高涵翔,白明,赵存瑞,赵晶,潘晨亮,张钲

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