急性心肌梗死经皮冠状动脉介入治疗术后并发脑出血的抗栓治疗管理:临床困境、循证证据与多学科管理策略Antithrombotic management of intracerebral hemorrhage complicating percutaneous coronary intervention in acute myocardial infarction: clinical dilemma, evidence synthesis, and multidisciplinary strategy
马贵清,马如超,陈刚,刘述,苏婧,宋瑞霞,林欣
摘要(Abstract):
急性心肌梗死患者接受经皮冠状动脉介入治疗后若并发急性脑出血,临床管理面临抗栓与止血之间的根本性矛盾。目前尚无专门针对该特殊人群的前瞻性研究或指南推荐,现有实践多借鉴脑卒中合并急性冠状动脉综合征的观察性数据或溶栓相关出血管理经验。在此背景下,建立基于风险分层的动态管理框架尤为迫切。本文旨在系统综述这一特殊临床场景下的管理策略,深入探讨该并发症的病理生理机制、风险评估、治疗决策中的风险权衡、替代性血运重建方案以及多学科协作模式,以期为临床医师提供决策参考,最终改善患者预后。
关键词(KeyWords): 急性心肌梗死;经皮冠状动脉介入治疗;脑出血;抗栓治疗;管理策略
基金项目(Foundation): 甘肃省自然科学基金专项(26JRRA814)
作者(Author): 马贵清,马如超,陈刚,刘述,苏婧,宋瑞霞,林欣
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