白剑,徐伟,李晓宏,沈文志,刘宇,陈诤,顾蓉,高玲

• 1:南京大学医学院附属鼓楼医院心血管内科

摘要(Abstract)：

目的比较压力感知导管和二代冷冻球囊消融治疗持续性心房颤动(房颤)的效果和安全性。方法回顾性连续入选2016年12月至2018年12月在南京大学医学院附属鼓楼医院首次行压力感知导管或二代冷冻球囊消融的持续性房颤患者201例,根据患者使用的手术方式不同分为压力感知导管组(146例)和二代冷冻球囊组(55例)。观察两组患者术中X线曝光时间、手术操作时间、手术相关并发症及术后1年房颤/心房扑动(房扑)/房性心动过速(房速)复发情况。结果两组患者各项基线资料指标比较,差异均无统计学意义(均P>0.05);二代冷冻球囊组手术操作时间短于压力感知导管组[(127.9±35.1)min比(158.3±48.5)min,P<0.001],而X线暴露时间长于压力感知导管组[(27.8±11.5)min比(12.1±6.3)min,P<0.001],差异均有统计学意义;两组患者各种手术并发症发生率比较,差异均无统计学意义(均P>0.05);压力感知导管组和二代冷冻球囊组患者术后1年房颤/房扑/房速的复发率分别为24.0%和25.5%,Log-rank检验比较两组患者无房颤/房扑/房速生存率差异无统计学意义(P=0.811)。结论使用压力感知导管或二代冷冻球囊消融治疗持续性房颤,疗效及安全性相当。

关键词(KeyWords)： 持续性心房颤动;肺静脉电隔离;射频消融;冷冻球囊消融

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金（81870291）

作者(Author): 白剑,徐伟,李晓宏,沈文志,刘宇,陈诤,顾蓉,高玲

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