钙化结节对行冠状动脉斑块旋磨术的严重钙化病变患者长期预后的影响Long-time outcomes of calcified nodule in heavily calcified lesions requiring rotational atherectomy
曹成富,王伟民,刘健,卢明瑜,马玉良,李琪
摘要(Abstract):
目的 探索钙化结节对行冠状动脉斑块旋磨术的严重钙化病变患者长期预后的影响。方法 连续性纳入2015年1月至2020年12月于北京大学人民医院因严重钙化病变行冠状动脉斑块旋磨术并在术中行血管内超声或光学相干断层成像的患者,根据靶病变是否存在钙化结节,分为钙化结节组和非钙化结节组,对比两组患者的长期预后。结果 共有81例患者纳入最终分析,其中钙化结节组35例,非钙化结节组46例。两组患者临床资料匹配,钙化结节组患者钙化病变长度[(32.5±13.5)mm比(22.3±9.5)mm,P<0.001]大于非钙化结节组,支架膨胀率[(76.5±6.6)%比(80.0±8.0)%,P=0.036]小于非钙化结节组,差异均有统计学意义。中位随访23(10,40)个月,钙化结节组患者主要不良心血管事件发生率显著高于非钙化结节组(22.9%比6.5%,P=0.034)。结论 对于行冠状动脉斑块旋磨术的严重钙化病变患者,存在钙化结节的患者长期预后劣于无钙化结节患者。
关键词(KeyWords): 钙化结节;冠状动脉斑块旋磨术;冠状动脉钙化病变;长期预后
基金项目(Foundation):
作者(Author): 曹成富,王伟民,刘健,卢明瑜,马玉良,李琪
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