肺动脉瓣狭窄行经皮肺动脉瓣球囊扩张治疗52例近期随访分析Clinical analysis of percutaneous balloon pulmonary valvuloplasty in the treatment of 52 patients with pulmonary stenosis
周红梅,张刚成,尚小珂,彭婷,邓晓娴
摘要(Abstract):
目的探讨经皮肺动脉瓣球囊扩张术(PBPV)治疗肺动脉瓣狭窄(PS)的安全性和有效性。方法选取武汉亚洲心脏病医院先心病中心2007年至2012年收治的单纯PS患者52例,其中男24例,女28例,年龄1~56(9.2±7.6)岁,体重10~60(17.3±8.9)kg。完善心电图、X线胸片、超声心动图检查,行右心导管检查及右心室造影并完成PBPV术。结果所有患者均手术成功。PBPV术后,导管测右心室肺动脉瓣跨瓣压差(13.8±7.7)mmHg(1 mmHg=0.133 kPa)较术前(86.3±27.6)mmHg显著下降,差异有统计学意义(P<0.01)。术中,1例(1.9%)出现心室颤动而发生阿斯综合征,1例(1.9%)突发呼吸、心跳骤停,24例(46.2%)出现一过性心律失常,1例(1.9%)低血压,1例(1.9%)心动过缓,1例(1.9%)氧饱和度下降,给予相应处理均好转;2例(3.8%)出现穿刺后血肿,2例(3.8%)术后反应性漏斗部狭窄。结论 PBPV术在肺动脉瓣狭窄患者中应用安全,效果好,并发症少,患者痛苦小,应作为该类患者的首选治疗方法。
关键词(KeyWords): 经皮肺动脉瓣球囊扩张术;肺动脉瓣狭窄;先天性心脏病;右心室肥厚;右心室流出道痉挛
基金项目(Foundation):
作者(Author): 周红梅,张刚成,尚小珂,彭婷,邓晓娴
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