王晶,刘博罕,穆洋,徐勇,智光,陈韵岱

• 1:中国人民解放军总医院心血管内科

摘要(Abstract)：

目的应用负荷超声心动图评价冠状动脉慢性完全闭塞病变介入治疗效果。方法46例慢性完全闭塞患者根据介入治疗结果分为开通组和未通组,并在介入治疗术前和随访6个月时分别完成低剂量多巴酚丁胺负荷试验,应用半定量方法测定静息和负荷状态下室壁运动积分指数(WMSI)。同时应用三维超声心动图测定左心室容积和左心室射血分数。结果两组患者基线状态一般临床资料和各项超声心动图资料差异均无统计学意义。开通组术后在射血分数[(60.00±3.22)%比(62.65±3.58)%,P=0.017]、负荷状态下WMSI[(1.42±0.37)比(1.32±0.36),P<0.001]与术前结果相比,均有显著改善;射血分数[(62.65±3.58)%比(57.7±5.61)%,P=0.001)]和负荷状态下WMSI[(1.32±0.36)比(1.62±0.47),P<0.001]与未通组相比,均有显著改善。结论低剂量多巴酚丁胺负荷超声心动图可有效评估慢性完全闭塞病变介入治疗效果。成功开通慢性完全闭塞病变血管对于左心室容积和左心室整体收缩功能以及负荷状态下室壁运动均有一定的改善作用。

关键词(KeyWords)： 慢性完全闭塞病变;经皮冠状动脉介入治疗;多巴酚丁胺负荷超声心动图;室壁运动积分;三维超声心动图

Abstract:

Keywords:

基金项目(Foundation): 解放军总医院科技创新苗圃项目(13KMZ01)

作者(Author): 王晶,刘博罕,穆洋,徐勇,智光,陈韵岱

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