经皮去肾神经术在高血压合并糖尿病患者中的应用Renal denervation in patients with hypertension and diabetes mellitus
朱友琦,白明,苏昱润
摘要(Abstract):
高血压与糖尿病被认为是导致心血管病发病率与死亡率最高的两大共病。糖尿病是一种病因复杂的代谢性疾病,尽管近年来其发病机制与治疗手段取得了显著进展,仍存在诸多未解问题。研究显示,交感神经系统过度激活在糖尿病的发生与发展中发挥关键作用。经皮去肾神经术(RDN)可有效降低交感神经活性,因此其在糖尿病管理中的潜在应用逐渐引起关注。近年来,RDN因在难治性高血压治疗中的疗效而受到肯定,越来越多研究开始探索其在糖尿病患者中的应用价值及潜在获益。本文将重点综述交感神经激活在糖尿病中的作用机制,RDN在糖尿病管理中的研究进展,并展望其未来的临床应用前景。
关键词(KeyWords): 经皮去肾神经术;糖尿病;交感神经活性;高血压
基金项目(Foundation):
作者(Author): 朱友琦,白明,苏昱润
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