陈茂,冯沅,唐红,魏薪,赵振刚,徐原宁,廖延标,黄德嘉

• 1:四川大学华西医院心内科

摘要(Abstract)：

目的分享经导管主动脉瓣植入术(TAVI)治疗重度主动脉瓣狭窄患者的经验。方法分析已完成TAVI患者的基线特征、术后血流动力学变化情况及临床结果。结果 2012年4月至2014年3月共36例患者于四川大学华西医院进行TAVI,平均年龄(73.9±7.2)岁,其中男24例(66.7%),平均欧洲心脏手术风险回归评分为(20.6±9.9)%。25例(69.4%)患者主动脉瓣叶形态呈二叶式畸形。TAVI成功35例(97.2%),4例(11.1%)需植入第2枚瓣膜。术后主动脉瓣平均跨瓣压差下降至(10.5±5.7)mmHg(1 mmHg=0.133 kPa),2例残余瓣周漏接近中度。术后30 d内死亡1例(2.8%),脑卒中2例(5.6%)。10例(27.8%)患者因出现Ⅲ度房室传导阻滞而植入了永久起搏器。中位随访时间323 d,除2例患者分别于术后374 d和680 d死于恶性肿瘤外,其余患者均保持无症状生存。结论对于不适合进行外科手术的二叶式和三叶式主动脉瓣重度狭窄患者,TAVI是可行、安全和有效的。

关键词(KeyWords)： 主动脉瓣狭窄;二叶式主动脉瓣;经导管主动脉瓣植入术

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 陈茂,冯沅,唐红,魏薪,赵振刚,徐原宁,廖延标,黄德嘉

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