解翠,吕慧,高奋,巩书文,朱国斌,边云飞,杨志明

• 1:山西医科大学第二医院心内科
• 2:湖北医药学院附属人民医院心内科

摘要(Abstract)：

目的本研究旨在明确与冠状动脉慢血流性心绞痛(CSFA)相关的危险因素。方法回顾性分析山西医科大学第二医院以心绞痛为主要症状的患者,行冠状动脉造影后采用TIMI血流帧数(TFC)将入选患者分为2组,CSFA组64例,冠状动脉及血流均正常组(对照组)64例。排除既往心肌病、瓣膜病等,搜集所有研究对象临床及血液生化相关指标,采用Logitistic回归分析,明确各种危险因素对CSFA的影响。结果与对照组相比,CSFA组吸烟史及男性患者较多,差异有统计学意义(P<0.05);尿酸、载脂蛋白B100(Apo B100)、总胆固醇/高密度脂蛋白(TC/HDL)、低密度脂蛋白(LDL)/HDL水平均高于对照组(P<0.01);载脂蛋白A1(Apo A1)/Apo B100水平低于对照组(P=0.008)。Logistic回归分析显示,尿酸是CSFA的危险因素(OR 1.009,95%CI 1.003~1.015,P=0.004)。结论血尿酸水平增高可能导致CSFA的发生。

关键词(KeyWords)： 冠状动脉造影;冠状动脉慢血流性心绞痛;危险因素;尿酸

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 解翠,吕慧,高奋,巩书文,朱国斌,边云飞,杨志明

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