64排螺旋CT冠状动脉成像在冠状动脉病变诊断中的临床研究Investigation of 64-slice computed tomography angiography in diagnosis of coronary artery disease
卢明瑜,刘传芬,刘健,王伟民,武靖,杜湘柯,胡大一
摘要(Abstract):
目的探讨和评价64排螺旋CT(MSCT)在冠心病诊断中的有效性。方法选取在3周内行64排MSCT和冠状动脉造影(CAG)检查的临床可疑或确诊冠心病的患者(两项检查平均间隔时间9d)114例,其中男性62例,平均年龄65岁。将MSCT和CAG检查结果进行分析,管腔狭窄≥50%定义为明显狭窄。结果在114例患者中,CAG检出至少有1处明显狭窄的患者106例,其中单支病变占33%(38例),多支病变占60%(68例)。MSCT检出其中的104例(诊断准确度95%)。按节段分析,MSCT诊断冠状动脉明显狭窄的灵敏度、特异度、阳性预测值、阴性预测值分别为87%、96%、86%、96%。以各冠状动脉分析,MSCT诊断冠状动脉明显狭窄的灵敏度、特异度、阳性预测值、阴性预测值分别为96%、94%、95%、96%。MSCT与CAG在发现冠状动脉明显狭窄上差异无统计学意义(P>0.05)。结论64排MSCT诊断冠状动脉狭窄的准确度较高,作为一种冠心病诊断的无创筛查手段,有广泛的临床应用价值。
关键词(KeyWords): 冠状动脉疾病;体层摄影术,螺旋计算机;冠状血管造影术
基金项目(Foundation):
作者(Author): 卢明瑜,刘传芬,刘健,王伟民,武靖,杜湘柯,胡大一
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