吴铿,游琼,郑锡锋,李腾,叶少强,莫海亮,黄瑞娜

• 1:广东医学院附属医院心血管内科

摘要(Abstract)：

目的评估急性心肌梗死(acute myocardial infarction,AMI)合并心源性休克(cardiogenic shock,CS)患者经肱动脉与股动脉路径进行主动脉内球囊反搏术(TBA-IABP与TFA-IABP)的有效性及安全性。方法纳入2010年6月至2011年12月期间在广东医学院附属医院行TBA-IABP及TFA-IABP治疗的AMI合并CS患者95例,将患者随机分为TBA-IABP组(46例)和TFAIABP组(49例)。比较两组患者住院期间临床事件的发生率。结果与TFA-IABP组相比,TBAIABP组IABP开始工作至CS缓解时间、总住院时间、穿刺点压迫时间均降低[(44±10.6)h比(65±12.5)h;(154±26.6)h比(236±34.2)h;(3±1.6)min比(25±10.2)min,P均<0.05];TBA-IABP组迷走神经反射、血肿和假性动脉瘤发生率也较TFA-IABP组低(2%比10%;2%比8%;0比4%,P均<0.05);相应TBA-IABP组CS抢救成功率明显高于TFA-IABP组(87%比73%,P=0.047)。TBA-IABP组有2例出现轻度远端肢体血运欠佳,但经解痉镇痛症状缓解。结论对AMI合并CS患者,TBA-IABP的血管并发症发生少,且CS抢救成功率高,其机制可能与TBAIABP有利于局部压迫止血、无体位限制(患者可半坐卧位)、患者痛苦小和心理压力轻(减少交感神经张力)有关,作为可选择的血管路径之一。

关键词(KeyWords)： 主动脉内球囊反搏术;肱动脉;股动脉;急性心肌梗死;心源性休克

Abstract:

Keywords:

基金项目(Foundation): 中国医师协会阳光心血管研究基金项目(SCRFCMDA201232)

作者(Author): 吴铿,游琼,郑锡锋,李腾,叶少强,莫海亮,黄瑞娜

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