血小板功能和基因检测指导下的抗血小板治疗进展
马依彤,谢翔
摘要(Abstract):
<正>急性冠状动脉综合征(acute coronary syndrome,ACS)是一种非常常见的冠状动脉粥样硬化性心脏病急性发作临床类型,包括ST段抬高ACS和非ST段抬高ACS,主要发病机制是斑块破裂继发血栓形成,从而导致心肌缺血缺氧或者发生坏死。因此,在ACS的治疗中,除了再灌注治疗外,抗栓药物治疗也发挥着重要的作用。目前的抗栓药物主要有两大类,抗血小板类药物和抗凝血酶类药物。抗血小板药物主要包括阿司匹林、噻吩并吡啶类衍生物和血小板蛋白(GPI)Ⅱb/Ⅲa拮抗剂等;抗凝血酶类药物主要包括肝素、低分子肝素和维生素K拮抗剂等。另外,又
关键词(KeyWords): 急性冠状动脉综合征;抗血小板治疗
基金项目(Foundation): 国家自然科学基金资助项目(81160017)
作者(Author): 马依彤,谢翔
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