丁建,李赛男,金震,张洁,张诗蓓,左中印,刘子辰,丁明英,梁明,孙鸣宇,王祖禄

• 1:中国人民解放军北部战区总医院心内科

摘要(Abstract)：

目的 本研究旨在利用IntellaNav MiFi OI导管对离体猪心进行局部阻抗（LI）指导下的消融，探究LI下降与组织消融损伤范围之间的关系。方法 选取10只新鲜离体猪心，在30 W、40 W、50 W功率下进行消融，至LI下降15Ω、20Ω、25Ω、30Ω时终止放电，记录并比较消融前和消融结束时LI和射频消融仪阻抗（GI）、消融时间和消融损伤范围。结果 LI下降幅度与消融损伤的表面损伤宽度、最大损伤宽度、最大损伤深度及最大宽度处的深度之间均存在正相关关系（r=0.594,P<0.001;r=0.544,P<0.001;r=0.852,P<0.001;r=0.508,P<0.001），且与最大损伤深度的相关性最强。GI下降与消融损伤的表面损伤宽度、最大损伤宽度、最大损伤深度及最大宽度处的深度之间无显著相关性或仅存在弱相关性（r=0.124,P=0.186;r=0.222,P=0.017;r=0.360,P<0.001;r=0.203,P=0.029）。在各预期LI下降组中，消融功率30W、40W、50W所得到的消融损伤范围差异均无统计学意义，而消融所需时间差异均有统计学意义，消融功率30 W时达到预期LI下降的所需消融时间最长，50 W时所需消融时间最短。结论 LI下降与消融损伤范围存在正相关，且与最大损伤深度相关性最强，而GI下降与消融损伤范围之间相关性弱。消融功率不影响LI下降与消融损伤范围之间的关系，但是高功率可以缩短消融时间。

关键词(KeyWords)： 局部阻抗;射频消融仪阻抗;组织损伤范围;功率

Abstract:

Keywords:

基金项目(Foundation): 辽宁省科学技术计划项目（2020JH1/10300002）

作者(Author): 丁建,李赛男,金震,张洁,张诗蓓,左中印,刘子辰,丁明英,梁明,孙鸣宇,王祖禄

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