应用心脏磁共振成像评估冠状动脉慢性完全闭塞病变供血心肌活性研究Evaluation of myocardium viability by cardiac magnetic resonance in patients with chronic total occlusion lesions
杨雪瑶,栗佳男,韩烨,贺毅,张丽君,王月丽,宋现涛
摘要(Abstract):
目的通过心脏磁共振成像(CMR)结果分析冠状动脉慢性完全闭塞(CTO)病变患者的心肌室壁运动和心肌存活情况及其与CTO血管的对应关系。方法入选2014年12月至2017年11月于北京安贞医院行冠状动脉造影确诊至少有1支血管存在CTO病变的患者128例,入院后均行CMR检查。将左心室划分为17个心肌节段,对每个心肌节段进行室壁运动及延迟强化透壁程度评分,并记录CMR测得的左心室射血分数(LVEF)、收缩末期容积(ESV)、舒张末期容积(EDV)。结果 149支CTO血管供应区域中,仅有11.5%的心肌节段透壁梗死,而58.6%的心肌节段不存在心肌梗死,延迟强化透壁程度≥75%的患者的LVEF最低,EDV及ESV最高。结论 CMR检出大多数CTO患者存在不同程度的室壁运动异常及心肌梗死。透壁性心肌梗死患者存在明显心功能下降及心室重构,但透壁性心肌梗死患者仅占很小一部分。
关键词(KeyWords): 心脏磁共振成像;存活心肌;慢性完全闭塞;冠状动脉粥样硬化性心脏病
基金项目(Foundation): 国家自然科学基金(81501486、81671650);; 首都临床特色应用研究与成果推广(Z161100000516139);; 首都卫生发展科研专项(自主创新2018-2-2063)
作者(Author): 杨雪瑶,栗佳男,韩烨,贺毅,张丽君,王月丽,宋现涛
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