X线下联合经胸超声心动图经皮单根血管入径介入封堵治疗动脉导管未闭的临床研究Clinical study on the percutaneous occlusion with single vascular approach of patent ductus arteriosus by X-ray combined with transthoracic echocardiography
刘媛媛,包敏,张明明,王利军,王宏茂,石琳,郑春华
摘要(Abstract):
目的探究X线下联合经胸超声心动图经皮单根血管入径介入封堵治疗动脉导管未闭(PDA)的安全可行性。方法纳入2017年10月至2019年12月首都儿科研究所附属儿童医院导管室完成经典经皮介入封堵PDA治疗(造影组)和X线下联合经胸超声心动图经皮介入封堵PDA治疗(超声组)病例。两组患儿均用超声心动图和X线评估封堵效果,对比两组的手术时长、对比剂用量及射线剂量等。结果患儿年龄6个月~11岁,体重8~40 kg。超声组72例,造影组14例。所有患儿均一次封堵成功。超声组穿刺单根血管的有62例,造影组均穿刺两根血管,所有病例均无血管并发症。超声组手术时间为[(52.1±22.8)min比(111.0±42.4)min,P=0.030]、射线剂量[(25.4±19.0)mGy比(123.7±55.6)mGy,P<0.001]、对比剂用量[(0.2±1.2)ml比(42.5±14.4)ml,P<0.001]显著低于造影组,差异均有统计学意义。结论 X线下联合经胸超声心动图经皮单根血管入径介入封堵治疗PDA安全可行。
关键词(KeyWords): 先天性心脏病;动脉导管未闭;介入封堵术;经胸超声心动图
基金项目(Foundation):
作者(Author): 刘媛媛,包敏,张明明,王利军,王宏茂,石琳,郑春华
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