建立胸痛中心对不同来院方式ST段抬高急性心肌梗死患者进门-球囊时间的影响The impacts of the establishment of chest pain center on the door-to-balloon time in patients with ST-elevation myocardial infarction by different transfer ways to hospital
易绍东,向定成,段天兵,秦伟毅,彭雄,张金霞
摘要(Abstract):
目的探讨胸痛中心(CPC)对不同来院方式接受直接经皮冠状动脉介入治疗(PPCI)的ST段抬高急性心肌梗死(STEMI)患者进门-球囊(D-to-B)时间的影响。方法根据来院方式不同将CPC成立前、后接受PPCI的STEMI患者分别分为自行来院组[A1组(52例)和A2组(65例)]、呼叫"120"组[B1组(31例)和B2组(92例)]、非经皮冠状动脉介入治疗(PCI)医院转诊组[C1组(23例)和C2组(552例)],比较同一来院方式的两组间D-to-B时间和D-to-B达标率的变化,分析延迟原因。结果 A1、A2组平均D-to-B时间分别是(123±78)min和(140±123)min,达标率分别为44.2%和46.2%,两组间比较,差异均无统计学意义(P>0.05);B2组平均D-to-B时间显著短于B1组[(89±66)min比(155±115)min,P<0.05],而达标率显著高于B1组(69.6%比32.3%,P<0.05);C2组平均D-to-B时间显著短于C1组[(77±43)min比(337±662)min,P<0.05],达标率显著高于C1组(75.7%比21.7%,P<0.05)。自行来院组的主要延迟原因是签署知情同意书时间过长,呼叫"120"组和非PCI医院转诊组的主要延迟原因是导管室占台。结论区域协同救治模式CPC显著缩短了呼叫"120"和转诊入院患者的D-to-B时间,但需加强对自行来院途径的院内流程优化。
关键词(KeyWords): 心肌梗死;血管成形术;医师诊疗模式;胸痛中心
基金项目(Foundation): 广东省科技计划重大项目(2012A080104020);; 广东省科技计划项目(2012B031800182);; 广州市科技计划专项(2012J4300107);; 广州市重点实验室建设专项(穗科信字[2013]163-15)
作者(Author): 易绍东,向定成,段天兵,秦伟毅,彭雄,张金霞
参考文献(References):
- [1]Bradley EH,Nallamothu BK,Stern AF,et al.The Door-to-Balloon Alliance for Quality:who joins national collaborative efforts and whyJt Comm J Qual Patient Saf,2009,35:93-99.
- [2]“胸痛中心”建设中国专家共识组.“胸痛中心”建设中国专家共识.中华危重症医学杂志(电子版),2011,4:381-393.
- [3]向定成,秦伟毅,周民伟.胸痛中心建设规范与实践.北京:人民军医出版社,2013:57.
- [4]向定成,段天兵,秦伟毅,等.建立规范化胸痛中心对直接经皮冠状动脉介入治疗患者进门-球囊扩张时间及预后的影响.中华心血管病杂志,2013,41:1-4.
- [5]罗望胜,向定成,张金霞,等.远程实时传输12导联心电图对急性ST段抬高性心肌梗死患者的院前诊断价值.中华急诊医学杂志,2013,22:669-674.
- [6]Nallamothu BK,Bates ER,Herrin J,et al.Times to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States:National Registry of Myocardial Infarction(NRMI)-3/4 analysis.Circulation,2005,111:761-767.
- [7]Zhang Q,Zhang RY,Qiu JP,et al.Impact of different clinical pathways on outcomes of patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention:the RAPID-AMI study.Chin Med J(Engl),2009,122:636-642.
- [8]van de Loo A,Saurbier B,Kalbhenn J,et al.Primary percutaneous coronary intervention in acute myocardial infarction:direct transportation to catheterization laboratory by emergency teams reduces door-to-balloon time.Clin Cardiol,2006,29:112-116.
- [9]易绍东,向定成.规范化胸痛中心建设及ST段抬高型心肌梗死区域协同救治经验交流与示范会纪要.中华心血管病杂志,2012,40:923-924.
- [10]Glickman SW,Shofer FS,wu MC,et al.Development and validation of a prioritization rule for obtaining an immediate 12lead electrocardiogram in the emergency department to identify STelevation myocardial infarction.Am Heart J,2012,163:372-382.
- [11]中国急性冠状动脉综合征多中心临床研究协作组.中国多省市急性冠状动脉综合征住院患者治疗现状与指南差距分析.中华心血管病杂志,2005,33:7.
- [12]Patrick T,Frederick G,Deborah D,et al.2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction.A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.J Am Coll Cardiol,2013,61:e78-e140.