孙月玲,苑淑丽,孙波,冯福宾

• 1:赤峰市第二医院心内二科

摘要(Abstract)：

目的评价国产BuMA生物降解药物涂层冠状动脉支架在冠心病小血管病变经皮冠状动脉介入治疗中的临床疗效及安全性。方法选择182例行经皮冠状动脉介入治疗(PCI)的冠心病患者,其中小血管病变组102例,大血管病变组80例,均置入BuMA生物降解药物涂层冠状动脉支架,比较观察手术成功率、术中并发症及在1~12个月随访期间的心绞痛、猝死、主要不良心脏事件(MACE)发生率及复查冠状动脉造影情况。结果大血管病变组和小血管病变组手术即刻成功率均为100%,两组共发现203处靶病变,共置入支架273枚。术中均无严重并发症发生。对入选182例患者进行出院后第1、3、6、12个月门诊随访发现,小血管病变组8例心绞痛复发,其中1例为糖尿病患者。大血管病变组5例复发心绞痛。于术后第6~9个月复查冠状动脉造影证实,小血管病变组2例分别为右冠状动脉主干、左前降支支架内远段再狭窄达75%~80%,大血管病变组1例为左前降支支架近端再狭窄75%。两组心绞痛复发、冠状动脉造影支架内再狭窄及靶病变血运重建主要MACE发生率的差异均无统计学意义。两组均未出现迟发性支架内血栓、无心肌梗死及猝死。结论国产BuMA生物降解药物涂层冠状动脉支架应用于冠心病小血管病变介入治疗安全、有效,疗效不逊于用于冠心病大血管病变时。

关键词(KeyWords)： 冠心病;小血管;大血管;介入治疗;BuMA生物降解药物涂层冠状动脉支架

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 孙月玲,苑淑丽,孙波,冯福宾

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