陈汉阳,刘文娴,张丽洁

• 1:福建省华安县中医院
• 2:首都医科大学附属北京安贞医院
• 3:首都医科大学附属北京安贞医院心内科

摘要(Abstract)：

目的探讨2型糖尿病(T2DM)合并冠心病(CAD)患者糖化血红蛋白(HbA1c)水平与冠脉病变特点的关系。方法 289例T2DM合并CAD患者,按照HbA1c水平分为两组,A组103例(HbA1c<7%),B组186例(HbA1c≥7%),对两组患者冠脉造影结果进行Gensini积分并对比分析。结果 B组患糖尿病史、吸烟比例和微量白蛋白尿阳性率均高于A组,空腹血糖、总胆固醇、甘油三酯、血尿酸水平也高于A组;从冠脉病变看,三支病变、弥漫性病变、冠脉C型病变,B组显著高于A组,且B组冠脉病变Gensini积分较高(P<0.01),HbAlc水平与Gensini积分呈正相关(P<0.01)。结论 T2DM合并CAD患者HbAlc水平高,其冠脉病变呈现复杂和严重的临床特点。因此,T2DM合并CAD患者应尽早积极有效地控制血糖水平,对于冠心病的防治甚为重要。

关键词(KeyWords)： 糖尿病,2型;冠状动脉疾病;血红蛋白A,糖基化

Abstract:

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基金项目(Foundation):

作者(Author): 陈汉阳,刘文娴,张丽洁

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