郭楚娴,杨龙,霍照美,杨英,赵义冬,何炯红,田野,田龙海

• 1:贵州医科大学
• 2:贵州省人民医院心内科

摘要(Abstract)：

目的探讨饮酒与非瓣膜性心房颤动(房颤)患者左心耳血栓形成的关系。方法连续入选2016年1月至2018年11月于贵州省人民医院拟行导管射频消融术的房颤患者436例,收集病史资料和实验室检查结果,并采用CHA_2DS_2-VASc评分进行卒中风险评估。通过经食管超声心动图判断有无左心耳血栓形成,并据此将患者分为血栓组(55例)和无血栓组(381例)。探讨饮酒与左心耳血栓形成的关系。结果 436例非瓣膜性房颤患者中,55例(12.6%)存在左心耳血栓。血栓组患者饮酒比例均高于无血栓组(47.3%比12.1%,P<0.001)。logistic多因素回归分析结果显示,校正混杂因素后,年龄、非阵发性房颤、饮酒、房颤病程及CHA_2DS_2-VASc评分为房颤患者左心耳血栓形成的独立危险因素,其中饮酒为最强的独立危险因素(OR 14.673,95%CI 6.021～35.759,P<0.001)。结论饮酒是非瓣膜性房颤患者左心耳血栓形成的独立危险因素。

关键词(KeyWords)： 酒精;左心耳;血栓形成;非瓣膜性心房颤动;危险因素

Abstract:

Keywords:

基金项目(Foundation): 贵州省科技支撑计划[黔科合支撑（2017）2885];; 贵州省科技平台及人才团队计划（黔科合平台人才[（2017）5405]）

作者(Author): 郭楚娴,杨龙,霍照美,杨英,赵义冬,何炯红,田野,田龙海

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