冠状动脉支架置入术对冠心病患者术后早期血清抵抗素水平的影响Effect of coronary stenting on serum resistin levels
周永勤,黄友敏,王霞,张国庆,李勇
摘要(Abstract)：
目的评价经皮冠状动脉支架置入术(CSI)对血清抵抗素水平的影响。方法选择2007年7月至2008年5月在我院行CSI的40例患者为研究对象(CSI组),同时选择一组同期进行冠状动脉造影(CAG)的40例患者作为对照(CAG组)。采用酶联免疫(ELISA)法检测血清抵抗素和超敏C反应蛋白(Hs-CRP)含量,并分别于CSI或CAG术前及术后1 h、6 h、24 h采集静脉血进行血清抵抗素和Hs-CRP含量的测定。结果CSI组患者血清抵抗素水平术后6 h显著高于术前(30.4±9.2μg/L比23.4±6.4μg/L,t=9.03,P<0.01),术后24 h Hs-CRP含量显著高于术前(15.2±4.1 mg/L比7.4±3.4 mg/L,P<0.01),并达到高峰。CAG组患者造影后与造影前比较,血清抵抗素水平差异无统计学意义(P>0.05)。结论冠状动脉支架置入术后血清抵抗素水平升高,提示术后有炎症刺激反应。
关键词(KeyWords)： 冠状动脉疾病;支架;抵抗素
基金项目(Foundation):
作者(Author): 周永勤,黄友敏,王霞,张国庆,李勇
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