杨威,张抒扬,沈珠军,范中杰,曾勇,金晓峰

• 1:中国医学科学院北京协和医学院北京协和医院心血管内科

摘要(Abstract)：

目的评价肾动脉支架治疗肾动脉粥样硬化性狭窄的临床疗效,并用肾图评价1年后患者的分肾功能。方法收集2006年1月至2009年8月在北京协和医院心内科接受一侧或双侧肾动脉支架治疗的106例肾动脉粥样硬化性狭窄患者,采集患者的血压、抗血压药物种类、肌酐、估计肾小球滤过率(eGFR)等临床资料,术后随访6至24个月。结果肾动脉支架术后,患者血压明显降低或稳定,由术前的(160±19)/(86±12)mmHg降至术后6个月的(135±17)/(78±11)mmHg,术后12个月为(138±16)/(77±9)mmHg,术后24个月为(135±14)/(75±10)mmHg。术后6个月的脉压也有明显的下降。所服降压药的种类术前为(2.85±0.73)种,术后6个月为(2.13±0.86)种,术后12个月为(2.19±1.12)种,术后24个月为(2.61±0.87)种。患者肌酐及eGFR无明显变化或轻度降低;而1年后肾图结果显示,部分(11.7%)患者支架侧肾GFR水平稳定或轻度增加,而未支架侧肾GFR水平均有一定程度的降低。结论肾动脉支架重建血运能明显改善肾动脉粥样硬化狭窄患者的血压情况,支架术后单侧的肾功能无明显的改善。

关键词(KeyWords)： 肾动脉梗阻;支架;高血压;肾功能不全;肾小球滤过率

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 杨威,张抒扬,沈珠军,范中杰,曾勇,金晓峰

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