两种危险因素定量评估系统对不典型胸痛患者冠状动脉病变程度预测的对比研究Comparative study of two prediction scoring systems on patients with suspected coronary heart disease
周志明,郭永和,贾德安,张琳琳,胡宾,赵敏捷,周玉杰
摘要(Abstract):
目的探讨两种危险因素定量评估系统在预测不典型胸痛患者冠状动脉病变程度中的作用。方法入选疑诊冠心病(CHD)不典型胸痛患者272例,行冠状动脉造影(CAG)检查诊断为CHD的患者94例(CHD组),非CHD患者178例(非CHD组)。收集患者资料,分别导入PROCAM风险评分系统和冠状动脉病变程度预测评分系统(SCP评分系统),计算相应积分,采用Spearman法分析两种评分系统积分与冠状动脉SYNTAX积分间的相关关系,利用工作特征曲线(ROC)评价各评分系统的效能。结果所有患者的PROCAM积分为6.00~77.00(41.76±19.91)分,随着积分数值增加,其冠状动脉SYNTAX积分升高,两者呈正相关(rs=0.420,P=0.023)。所有患者的SCP积分为1.00~13.00(8.64±3.42)分,其积分数值亦与冠状动脉SYNTAX积分呈正相关(rs=0.482,P=0.016),且SCP积分的相关性更高。PROCAM积分ROC的曲线下面积(AUC)为0.770(P=0.007),SCP积分ROC的AUC为0.733(P=0.012),PROCAM积分ROC的AUC较大。结论两个评分系统均能对疑诊CHD患者的冠状动脉病变程度进行有效预测,与CAG结果均有较好的相关性。
关键词(KeyWords): 冠心病;PROCAM风险评估系统;SCP评分系统;SYNTAX积分
基金项目(Foundation): 北京市医院管理局临床医学发展专项经费资助(ZYLX201303);; 国家临床重点专科建设项目经费资助(2013—2014年度)
作者(Author): 周志明,郭永和,贾德安,张琳琳,胡宾,赵敏捷,周玉杰
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