经皮冠状动脉介入治疗术后消化道损伤的预防及消化道出血处理流程专家研讨会会议纪要
魏盟,郑松柏,郭新贵,俞丽芬,戴秋艳,沈节艳,林江,杨伟,殷兆芳,魏毅东
摘要(Abstract):
<正>经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)作为一项有效的治疗技术已经广泛应用于稳定型冠状动脉疾病和急性冠状动脉综合征(acute coronar y syndrome,ACS)的治疗。2016年我国完成PCI共计666 495例,仅次于美国,位居世界第二~([1])。为了防止缺血并发症,PCI术后常使用抗血栓药物。
关键词(KeyWords): 经皮冠状动脉介入治疗;消化道损伤;质子泵抑制剂
基金项目(Foundation):
作者(Author): 魏盟,郑松柏,郭新贵,俞丽芬,戴秋艳,沈节艳,林江,杨伟,殷兆芳,魏毅东
参考文献(References):
- [1]刘浩生.2016年中国大陆地区冠心病介入治疗数据分享.中华医学信息导报,2017,32(10):17.
- [2]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.抗血小板治疗中国专家共识.中华心血管病杂志,2013,41(3):183-194.
- [3]Levine GN,Bates ER,Bittl JA,et al.2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease:a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines:an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention,2011ACCF/AHA guideline for coronary artery bypass graft surgery,2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease,2013 ACCF/AHA guideline for the management of STelevation myocardial infarction,2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes,and 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery.Circulation,2016,134(10):e123-e155.
- [4]Cavender MA,Rao SV.Bleeding associated with current therapies for acute coronary syndrome:what are the mechanisms?J Thromb Thrombolysis,2010,30(3):332-339.
- [5]Alexopoulos D,Xanthopoulou I,Davlouros P,et al.Mechanisms of nonfatal acute myocardial infarction late after stent implantation:the relative impact of disease progression,stent restenosis,and stent thrombosis.Am Heart J,2010,159(3):439-445.
- [6]Valqimiqli M,Bueno H,Byrne RA,et al,2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS.Kardiol Pol,2017,75(12):1217-1299.
- [7]Nishino M,Sugimoto M,Kodaira C,et al.Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric p H in healthy volunteers.Dig Dis Sci,2010,55(6):1627-1636.
- [8]Sugimoto M,Nishino M,Kodaira C,et al.Impact of acid inhibition on esophageal mucosal injury induced by low-dose aspirin.Digestion,2012,85(1):9-17.
- [9]Sugimoto M,Nishino M,Kodaira C,et al.Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole.J Clin Pharmacol,2010,50(3):320-330.
- [10]Yeomans ND,Lanas AI,Talley NJ,et al.Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin.Aliment Pharmacol Ther,2005,22(9):795-801.
- [11]Li L,Geraghty OC,Mehta Z,et al.Age-specific risks,severity,time course,and outcome of bleeding on long-term antiplatelet treatment after vascular events:a population-based cohort study.Lancet,2017,390(10093):490-499.
- [12]Grove EL,Wurtz M,Schwarz P,et al.Gastrointestinal events with clopidogrel:a nationwide population-based cohort study.J Gen Intern Med,2013,28(2):216-222.
- [13]Di Minno A,Spadarella G,Prisco D,et al.Antithrombotic drugs,patient characteristics,and gastrointestinal bleeding:Clinical translation and areas of research.Blood Rev,2015,29(5):335-343.
- [14]Goto S,Huang CH,Park SJ,et al.Ticagrelor vs.clopidogrel in Japanese,Korean and Taiwanese patients with acute coronary syndrome--randomized,double-blind,phase III PHILO study.Circ J,2015,79(11):2452-2460.
- [15]Wallentin L,Becker RC,Budaj A,et al.Ticagrelor versus clopidogrel in patients with acute coronary syndromes.N Engl J Med,2009,361(11):1045-1057.
- [16]Mc Quaid KR,Laine L.Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials.Am J Med,2006,119(8):624-638.
- [17]Seddighzadeh A,Wolf AT,Parasuraman S,et al.Gastrointestinal complications after 3 months of dual antiplatelet therapy for drug-eluting stents as assessed by wireless capsule endoscopy.Clin Appl Thromb Hemost,2009,15(2):171-176.
- [18]Bhatt DL,Scheiman J,Abraham NS,et al.ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use.Am J Gastroenterol,2008,103(11):2890-2907.
- [19]Karim S,Ador-Dionisio ST,Karim M,et al.Assessment of safety of performing percutaneous coronary intervention after a recent episode of gastrointestinal bleeding.Acute Card Care,2016,18(1):1-6.
- [20]Genereux P,Giustino G,Witzenbichler B,et al.Incidence,Predictors,and impact of Post-Discharge bleeding af ter percutaneous coronary intervention.J Am Coll Cardiol,2015,66(9):1036-1045.
- [21]Bi Y,Gao R,Patel A,et al.Evidence-based medication use among Chinese patients with acute coronary syndromes at the time of hospital discharge and 1 year after hospitalization:results from the clinical pathways for acute coronary syndromes in China(CPACS)study.Am Heart J,2009,157(3):509-516,e501.
- [22]张亚梅,陈庆伟.PCI术后1年患者双联抗血小板药物治疗依从性随访研究.重庆医科大学学报,2011,36(4):503-506.
- [23]抗血小板药物消化道损伤的预防和治疗中国专家共识组.抗血小板药物消化道损伤的预防和治疗中国专家共识.中华内科杂志,2013,52(3):607-611.
- [24]陈韵岱,王建安,刘斌,等.药物涂层球囊临床应用中国专家共识.中国介入心脏病学杂志,2016,24(2):61-67.
- [25]Garcia Rodriguez LA,Barreales Tolosa L.Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population.Gastroenterology,2007,132(2):498-506.
- [26]Sugano K,Tack J,Kuipers EJ,et al.Kyoto global consensus report on Helicobacter pylori gastritis.Gut,2015,64(9):1353-1367.
- [27]郑松柏,姚健风.老年人质子泵抑制剂合理应用专家共识.中华老年医学杂志,2015,34(10):1-7.
- [28]Fujimoto K,Hongo M.Safety and efficacy of long-term maintenance therapy with oral dose of rabeprazole 10 mg once daily in Japanese patients with reflux esophagitis.Intern Med,2011,50(3):179-188.
- [29]Thjodleifsson B,Rindi G,Fiocca R,et al.A randomized,doubleblind trial of the efficacy and safety of 10 or 20 mg rabeprazole compared with 20 mg omeprazole in the maintenance of gastrooesophageal reflux disease over 5 years.Aliment Pharmacol Ther,2003,17(3):343-351.
- [30]Song H,Zhu J,Lu D.Long-term proton pump inhibitor(PPI)use and the development of gastric pre-malignant lesions.Cochrane Database Syst Rev,2014,(12):Cd010623.
- [31]Scott SA,Sangkuhl K,Stein CM,et al.Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and c lopidogrel therapy:2013 update.Clin Pharmacol Ther,2013,94(3):317-323.
- [32]Wedemeyer RS,Blume H.Pharmacokinetic drug interaction profiles of proton pump inhibitors:an update.Drug Saf,2014,37(4):201-211.
- [33]Sung JJ,Chan FK,Chen M,et al.Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding.Gut,2011,60(9):1170-1177.