药物涂层球囊应用于冠状动脉原发病变的研究进展
曾川锐,余家凤,刘映峰,缪绯
摘要(Abstract):
<正>目前,全球冠心病患病率处于持续上升阶段,占成人心血管病死亡原因的首位。据推算,中国现有冠心病患者1100万,2017年大陆地区冠心病介入治疗总例数为753 142例,较2016年增长13%[1]。自1977年实施全球第1例经皮冠状动脉腔内血管成形术(percutaneous transluminal coronary angioplasty,PTCA)以来,冠心病的介入治疗取得了许多重大进展。裸金属支架(bare-mental stent,BMS)的出现降低了PTCA后血管弹性回缩和急性闭塞的发生率[2]。随后药物洗脱支架(drugeluting stent,DES)的出现显著降低了支架内再狭窄(in-stent restenosis,ISR)的发生率,但仍存在支架内血栓形成和较长双联抗血小板治疗时间导致出血等严重并发症[3]。这些问题
关键词(KeyWords): 药物涂层球囊;冠心病;经皮冠状动脉介入治疗
基金项目(Foundation):
作者(Author): 曾川锐,余家凤,刘映峰,缪绯
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