张源,王君,汪智全,张睿,孙健,张澎湃,李毅刚,王群山

• 1:上海交通大学医学院附属新华医院心内科

摘要(Abstract)：

目的了解并分析心房颤动(房颤)患者射频消融术后生活质量及其影响因素。方法纳入2014年4月至2016年2月于上海交通大学医学院附属新华医院行单次射频消融术的房颤患者,应用SF-36生活质量调查表(SF-36量表)进行生活质量调查,对可能影响生活质量的因素进行分析。结果共250例患者纳入分析,射频消融术后患者SF-36量表基线及3个月后不同时间点各维度得分比较,差异无统计学意义(P>0.05),其中基线和术后3个月时生理健康(PCS)评分[(70.6±17.1)分比(72.9±10.7)分,P=0.078]、心理健康(MCS)评分[(70.9±12.3)分比(71.8±12.5)分,P=0.44]及SF-36量表总分[(70.8±13.0)分比(72.3±10.3)分,P=0.138]比较,差异均无统计学意义。单因素分析发现,射频消融术后房颤是否复发、吸烟、心功能、高血压病、服用的抗凝药物类型与生活质量相关。多因素分析发现,术后复发与生活质量(PCS,β=―3.162,P=0.036;MCS,β=―5.675,P=0.001;SF-36总分,β=―4.385,P=0.003)呈负相关,服用华法林与MCS(β=―4.020,P=0.014)呈负相关,吸烟与PCS(β=―3.129,P=0.037)呈负相关。结论射频消融术后3个月生活质量相对稳定,消融结果是影响其生活质量的主要因素,达比加群酯和吸烟对生活质量也有一定影响。

关键词(KeyWords)： 生活质量;射频消融术;心房颤动;SF-36量表

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目(81270259)

作者(Author): 张源,王君,汪智全,张睿,孙健,张澎湃,李毅刚,王群山

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