姜海滨,黄新苗,白元,陈翔,宗书峰,赵仙先,秦永文,刘宗军

• 1:第二军医大学附属长海医院心内科
• 2:上海中医药大学附属普陀区中心医院心内科

摘要(Abstract)：

目的测量在不同起搏频率下主动脉跨瓣压力阶差的变化,为经导管主动脉瓣置入手术确定适合的起搏参数。方法选取6只成年健康山羊,全麻下经股静脉将临时起搏电极送至右心室,连接临时起搏器,频率范围由150次/分递增至350次/分,以25次/分递增频率,测量在不同起搏频率下主动脉瓣上和瓣下的收缩压、舒张压和平均压,并计算压力阶差。结果收缩期主动脉跨瓣压力阶差随起搏频率的加快而升高,至250~300次/分时,由(-25.00±3.90)mm Hg上升至(11.17±10.85)到(13.50±3.89)mm Hg之间。舒张期跨瓣压力阶差随起搏频率的加快而降低,至250~300次/分时,稳定在(47.00±3.03)mm Hg到(43.83±2.93)mm Hg之间,压力阶差降幅达50.11%。结论 250~300次/分的起搏频率可有效地降低主动脉跨瓣压力阶差,既能保证动物的安全又可减少因压力阶差引起的瓣膜置入过程中的移位。

关键词(KeyWords)： 主动脉瓣;压力;心脏起搏,人工

Abstract:

Keywords:

基金项目(Foundation): 国家高科技研究发展计划(863计划,2006AA02Z4D7)

作者(Author): 姜海滨,黄新苗,白元,陈翔,宗书峰,赵仙先,秦永文,刘宗军

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