肺癌外科术后合并心房颤动患者的导管消融治疗Outcome of radiofrequency catheter ablation of atrial fibrillation in patients after lung cancer surgery
李松南,董建增,王璐,吴晓燕,闻松男,白融,刘念,龙德勇,喻荣辉,汤日波,桑才华,蒋晨曦,马长生
摘要(Abstract):
目的分析肺癌外科术后合并心房颤动(房颤)患者的临床及电生理特征,并评价此类患者接受导管消融治疗的效果。方法共入选14例肺癌外科术后合并房颤行导管消融的患者(观察组),按照1∶2随机选取同期入院消融的无肺部手术史的房颤患者作为对照组。所有患者均行导管消融,并随访心律失常复发情况。结果观察组患者体质量指数小于对照组[(23.6±3.1)kg/m2比(26.3±2.8)kg/m2,P=0.006],而合并糖尿病患者多于对照组(35.7%比7.1%,P=0.019);心房扑动或房性心动过速等在观察组患者中更为常见(64.3%比17.9%,P=0.002),且房颤相关症状更为严重。观察组患者的导管消融总手术时间及X线透视时间均高于对照组,差异有统计学意义[(197.5±73.2)min比(169.5±65.3)min,P<0.01]和[(45.7±28.5)min比(32.0±26.8)min,P<0.05]。随访期间,观察组和对照组分别有9例(64.3%)和14例(50.0%)复发心律失常。观察组患者单次消融的窦性心律维持率略低于对照组(35.7%比50.0%,P=0.185),但差异无统计学意义。结论对于肺癌外科术后合并房颤的患者,尽管单次消融成功率略低,导管消融仍是一种安全有效的治疗手段。
关键词(KeyWords): 心房颤动;导管消融;肺癌;外科术后
基金项目(Foundation): 北京市自然科学基金(7144207)
作者(Author): 李松南,董建增,王璐,吴晓燕,闻松男,白融,刘念,龙德勇,喻荣辉,汤日波,桑才华,蒋晨曦,马长生
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