何晨,唐晓芳,袁晋青,杨跃进,陈珏,尤士杰,吴元,李健军,刘海波,吴永建,姚民,秦学文,乔树宾,高润霖,陈纪林

• 1:武汉亚洲心脏病医院心内科
• 2:北京协和医学院中国医学科学院北京阜外心血管病医院

摘要(Abstract)：

目的评估男性与女性冠心病患者冠状动脉直径≤3.0mm病变的介入治疗特点及中期预后。方法入选2004年4月至2008年4月收住阜外医院并进行经皮冠状动脉介入治疗(PCI)术的患者共计1350例(1702处治疗病变),介入治疗血管为参照血管直径<3.0mm的自身冠状动脉首次介入治疗病变,其中男性1073例(79.6%),女性277例(20.5%)。随访严重不良心脏事件。结果与既往研究相比,临床特征与既往研究基本相符。造影结果,男性术后和随访狭窄程度略高,同时支架释放成功率略低。其余造影结果并未明显差异。平均随访(181.1±9.6)d后,男女两组患者之间严重不良心脏事件差异没有统计学意义(23.1%比22.9%,χ2=0.02,P=0.87),除冠状动脉旁路移植术(CABG)和死亡因女性样本量太小原因得出差异外,包括急性心肌梗死(0.37%比0.36%,χ2=0.003,P=0.95),再狭窄(16.6%比15.6%,χ2=0.68,P=0.41),晚期支架内血栓(0.56%比0.36%,χ2=1.15,P=0.28),再次血管重建(11.8%比13.4%,χ2=2.55,P=0.11)等各亚项差异皆无统计学意义。结论男女冠心病患者在冠状动脉直径相同和病变特点相似情况下,PCI术后女性和男性的中期预后差异无统计学意义。冠状动脉血管直径的差异,可能对PCI术后预后的性别差异中起着关键性的作用。

关键词(KeyWords)： 冠状血管直径;性别因素;血管成形术,经腔,经皮冠状动脉

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 何晨,唐晓芳,袁晋青,杨跃进,陈珏,尤士杰,吴元,李健军,刘海波,吴永建,姚民,秦学文,乔树宾,高润霖,陈纪林

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