急性冠状动脉综合征患者非罪犯斑块稳定性的研究进展
蔡恒烜,于波
摘要(Abstract):
<正>急性冠状动脉综合征(acute coronary syndrome,ACS)是目前导致冠心病患者死亡的首要病因。未来10年内,我国ACS患病及死亡人数仍将快速增长。尽管临床上采取积极的药物及冠状动脉介入等干预治疗策略,但我国城乡居民ACS发病率及死亡率仍呈上升趋势[1]。目前ACS诊断的金标准仍为冠状动脉造影,冠心病常规以冠状动脉造影来判定介入治疗的适应证及评估治疗效果,但造影获取的信息量十分有限,最大的缺陷是无法确定ACS前期病变,即易损斑块的特征性信息。有研究表明,动脉粥样硬化斑块组织成分以及结构特性决定其危险度,且影响冠心病患者预后[2]。既往研究认为,心血管急性事件的发生与冠状动脉狭窄程度密切相关[3]。近年
关键词(KeyWords): 非罪犯斑块;腔内影像学;急性冠状动脉综合征;形态学特征
基金项目(Foundation): 国家“十三五”课题:(2016YFC1301100);; 国家自然科学基金重大仪器研制项目(81827806)
作者(Author): 蔡恒烜,于波
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