“容量控制血运重建方法”在急性心肌梗死患者急诊介入治疗中应用4例报告并文献回顾
何冀芳,杨新春,吴霞,江世猛,刘宇,李江媛,徐世莹,王乐丰
摘要(Abstract):
<正>急性心肌梗死患者急诊介入治疗死亡率高达7%左右,心力衰竭发生率接近22%~([1])。冠状动脉血流恢复不可避免地引起心肌再灌注损伤(ischemic reperfusion injury,IRI),缺血程度和再灌注损伤相互作用,导致心肌再灌注前缺血损伤区域(area at risk,AAR)心肌细胞发生坏死,增加梗死面积。我们在后适应和逐渐适应的理论基础上提出"容量控制血运重建方法"的设想,2019年11月至2020年1月已经以此为指导进行4例急性下壁心肌梗死急诊介入治疗,评价可操作性和安全性。
关键词(KeyWords): 急性心肌梗死;缺血后适应;介入治疗;血运重建
基金项目(Foundation): 科技部国家重点研发计划(2016YFC1301102)
作者(Author): 何冀芳,杨新春,吴霞,江世猛,刘宇,李江媛,徐世莹,王乐丰
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