吴晓爽,王威,张瑜,高磊

• 1:中国人民解放军总医院第六医学中心心血管病医学部
• 2:安徽医科大学第二附属医院心血管内科
• 3:天津中医药大学中西医结合学院

摘要(Abstract)：

冠状动脉钙化病变是经皮冠状动脉介入治疗（PCI）中的主要挑战，常导致支架膨胀不全、贴壁不良等并发症，影响患者预后。光学相干断层成像（OCT）作为一种超高分辨率的血管内成像技术，能够精准评估钙化斑块的边界、厚度、长度等特征，为优化钙化病变的介入策略提供了关键依据。通过系统综述OCT对不同阶段钙化斑块的评估和风险预测，阐述基于OCT的“术前评估-术中指导-术后优化”标准化操作流程与诊疗应用的关键技术要点，包括术前评估钙化评分、术中斑块修饰策略选择及术后支架置入效果验证，总结最新循证证据与临床获益，并分析OCT联合其他影像模态及人工智能技术的发展趋势，从病理基础到临床实践，深入探讨其如何重塑钙化病变的治疗范式，并为未来技术创新提供理论依据。

关键词(KeyWords)： 光学相干断层成像;冠状动脉钙化;介入治疗

Abstract:

Keywords:

基金项目(Foundation): 北京市自然科学基金面上项目（7242138）;; 首都卫生发展科研专项项目（首发2024-2-5072）

作者(Author): 吴晓爽,王威,张瑜,高磊

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