吴佳纬,胡昊,李丹,陈鸿武,马礼坤

• 1:中国科学技术大学附属第一医院心内科

摘要(Abstract)：

目的观察高血压病对急性心肌梗死(acute myocardial infarction,AMI)并发心源性休克(cardiac shock,CS)患者在主动脉内球囊反搏(intra-aortic balloon pump,IABP)辅助下行急诊经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)预后的影响。方法回顾性分析2010年3月至2016年1月在中国科学技术大学附属第一医院心内科因AMI并发CS在IABP辅助下行急诊PCI的100例患者。根据是否有高血压病史分为高血压病组(57例)、非高血压病组(43例)。收集患者基线资料,比较两组患者围术期、术后3个月及1年的出血事件和主要不良心脑血管事件(major adverse cardiovascular and cerebrovascular events,MACCE),包括支架内血栓形成、支架内再狭窄、再发心肌梗死、心血管事件死亡、卒中及全因死亡事件发生情况。结果两组患者年龄、性别、慢性肾功能不全比例、吸烟史、心血管疾病家族史、术前血红蛋白水平、血小板计数比较,差异均无统计学意义(均P>0.05)。高血压病组合并2型糖尿病比例(33.3%比14.0%,P=0.027)、卒中史比例(24.6%比2.3%,P=0.002)均大于非高血压病组,差异均有统计学意义。与非高血压病组相比,高血压病组围术期、术后3个月及1年的大出血事件发生率、心血管事件死亡率、卒中比例、全因死亡率及总MACCE发生率较高,但差异均无统计学意义(均P>0.05)。Cox多因素回归分析结果显示,高血压病与AMI并发CS患者在IABP辅助下行急诊PCI的心血管事件死亡率及全因死亡率无显著相关性。结论虽然高血压病对AMI并发CS患者在IABP辅助下行急诊PCI预后的影响不显著,但仍需对合并高血压病的患者进行监护,警惕出血事件和MACCE的发生。

关键词(KeyWords)： 高血压病;急性心肌梗死;心源性休克;主动脉内球囊反搏

Abstract:

Keywords:

基金项目(Foundation): 安徽省公益性技术应用研究联动计划(15011d04032);; 安徽省科技攻关计划(1604a0802074)

作者(Author): 吴佳纬,胡昊,李丹,陈鸿武,马礼坤

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