906例患者中冠状动脉内多普勒检查的安全性The safety of intracoronary Doppler flow meamsurement in 906 patients
钱菊英,葛均波,沈学东,陈灏珠,M.Haude,D.Baumgart,R.Erbel
摘要(Abstract)：
目的 是评价采用冠脉内多普勒导丝FloWire 进行冠脉内血流速度测定的安全性。方法 从 1993年到 1998年 ,共有 90 6例病人 (男性 70 4例 ,平均年龄 5 6 8± 10 8岁 )行冠脉内多普勒血流速度测定 ,血流描计仪采用CardiometricsFloMap ,多普勒导丝为 0 0 14英寸或 0 0 18英寸的FloWire ,为测定冠脉血流储备 ,采用冠脉内注射罂粟碱 (90例病人 ,右冠状动脉 8mg,左冠状动脉 12mg)或腺苷 (右冠状动脉 12 μg,左冠状动脉 18μg)诱发冠状动脉的最大扩张。 结果 在所有研究病人中 ,82 9例为非心脏移植病人 ,其中 6 17例为诊断性冠状动脉造影 (Ⅰ组 ) ,2 12例为冠脉内介入治疗病人 (Ⅱ组 ) ,77例为心脏移植术后病人 (C组 )。 90 6例病人中共有 2 7例 (2 98% )发生与多普勒血流测定有关的心血管并发症。在冠脉内注射腺苷后 ,15例病人 (1 6 6 % )发生较严重的短暂的心动过缓 (心脏停搏或Ⅱ度到Ⅲ度的房室传导阻滞 ) ,其中 14例发生在右冠状动脉 ,1例在左前降支。在多普勒导丝的送入过程中 ,9例 (0 99% )发生冠脉痉挛 (5例在右冠状动脉 ,4例在左冠状动脉 )。两例 (0 2 2 % )检查过程中发生室颤 (其中一例为冠脉内注射罂粟碱后 ,另一例为急性下壁心梗右冠状动脉急症球囊成形术后 ) ,低血压伴随心动过缓 1例 ,
关键词(KeyWords)： 冠状动脉;多普勒;安全性
基金项目(Foundation):
作者(Author): 钱菊英,葛均波,沈学东,陈灏珠,M.Haude,D.Baumgart,R.Erbel
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