姚义安,来晏,汤佳旎,叶梓,陈飞,丁可可,平凡,刘学波

• 1:同济大学附属同济医院心内科

摘要(Abstract)：

目的探讨右冠状动脉起源于左冠状动脉窦(RCAOL)血管内超声(IVUS)的影像学特征及RCAOL患者支架置入的可行性。方法前瞻性纳入2016年7月至2018年8月同济大学附属同济医院心内科冠状动脉造影证实RCAOL患者42例,分析RCAOL支架术前及术后即刻的IVUS影像学特征。结果 RCAOL患者42例中,男性更为多见(83.3%),典型胸痛患者占26.2%,以晕厥为首发症状的患者比例为19.0%。受压最严重节段与参考节段舒张期外弹力膜(EEM)面积比较,差异有统计学意义[(10.3±2.2)mm~2比(12.6±2.5)mm~2,P<0.001],但是管腔面积比较,差异无统计学意义[(9.5±2.3)mm~2比(10.3±1.8)mm~2,P=0.678];斑块负荷比较,差异有统计学意义[(19.7±6.0)%比(25.1±5.1)%,P<0.001]。而在受压最严重节段,收缩期受压指数(CI)较参考节段显著变化[(0.42±0.05)比(0.92±0.03),P<0.001]。从典型症状(胸痛及晕厥)患者19例与非典型症状患者23例的比较,病变长度[(8.7±1.9)mm比(6.9±1.0)mm,P<0.001]及收缩期CI(0.37±0.03)比(0.45±0.03),P<0.001]比较,差异均有统计学意义。对19例(45.2%)典型症状(胸痛及晕厥)IVUS见术后支架内横截面积较术前舒张期管腔面积,差异无统计学意义[(10.7±0.8)mm~2比(10.0±2.4)mm~2,P=0.667];但收缩期CI明显改变,较术前受压最严重节段增高,差异有统计学意义[(0.93±0.02)比(0.37±0.03),P<0.001]。结论 IVUS可动态观察RCAOL患者血管的影像特征,受压最重部位CI及受压节段长度可能是临床事件的独立预测因素。。

关键词(KeyWords)： 右冠状动脉起源于左冠状动脉窦;血管内超声;支架置入术

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 姚义安,来晏,汤佳旎,叶梓,陈飞,丁可可,平凡,刘学波

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