于扬,张宝娓,童琳,丁文惠,霍勇

• 1:北京大学第一医院心内科

摘要(Abstract)：

目的探讨55岁以下冠心病患者踝臂脉搏波传导速度(brachial-ankle pulse wave velocity,baPWV)的变化及影响因素。方法选择2010年2月至2012年1月经冠状动脉造影确诊为冠心病的204例患者(年龄≤55岁),采用动脉硬化测定仪测定双侧肢体的baPWV,并以baPWV≥14m/s为动脉僵硬度增高。统计患者动脉僵硬度异常的检出率,应用多因素分析筛选baPWV的影响因素。结果动脉僵硬度增高检出率58.3%,baPWV增高组患者收缩压水平显著高于baPWV正常组患者(t=3.016,P<0.01),女性患者baPWV水平显著高于男性患者(t=2.188,P<0.05)。baPWV与收缩压(r=0.343,P<0.001)、舒张压(r=0.194,P<0.05)、三酰甘油(r=0.166,P<0.05)、总胆固醇(r=0.188,P<0.05)呈正相关。多元线性回归分析显示女性、收缩压和三酰甘油是baPWV的独立影响因素。结论 55岁以下冠心病患者动脉僵硬度异常率较高,女性、收缩压和三酰甘油是55岁以下冠心病患者baPWV升高的独立影响因素。

关键词(KeyWords)： 冠状动脉疾病;脉搏波传导速度;因素分析,统计学

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 于扬,张宝娓,童琳,丁文惠,霍勇

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