单纯主动脉瓣反流经股动脉主动脉瓣置换中国专家共识2023Chinese expert consensus on trans-femoral transcatheter aortic valve replacement for pure aortic regurgitation 2023
摘要(Abstract):
经导管主动脉瓣置换术(TAVR)最初被应用于治疗主动脉瓣狭窄(AS),随后逐渐拓展到主动脉瓣反流(AR)治疗领域。国内外学者探索使用已上市的经股动脉TAVR(TF-TAVR)瓣膜以“超适应证”方式治疗AR患者,结果显示可作为外科手术高危患者的另一选择。但AR患者相较于AS解剖结构、瓣膜选择、操作方式以及并发症有其不同的特点,总体上使用已上市的TF-TAVR瓣膜治疗AR手术难度大,成功率较AS低。为了促进我国TF-TAVR治疗AR的安全、规范、健康发展,为该技术的临床使用提供合规性支持和技术指导,中国医师协会心血管内科医师分会结构性心脏病学组编写了该共识。执笔专家团队针对AR患者TF-TAVR临床实践中的重点及难点,结合所检索到文献(截至2023年9月1日)的证据力度,梳理出9个核心问题并做出深入分析,形成9个核心观点,涵盖适应证、瓣膜选择、术前评估、术中操作要点、并发症防治、术后管理等方面。
关键词(KeyWords): 经导管主动脉瓣置换术;主动脉瓣反流;经股动脉
基金项目(Foundation):
作者(Author):
参考文献(References):
- [1]中国医师协会心血管内科医师分会结构性心脏病专业委员会.经导管主动脉瓣置换术中国专家共识(2020更新版)[J].中国介入心脏病学杂志,2020,28(6):301-309.DOI:10.3969/j.issn.1004-8812.2020.06.001.
- [2]中国医师协会心血管内科医师分会结构性心脏病专业委员会.中国经导管主动脉瓣置换术临床路径专家共识(2021版)[J].中国介入心脏病学杂志,2022,30(1):7-16.DOI:10.3969/j.issn.1000-3614.2022.01.002.
- [3]Vahanian A,Beyersdorf F,Praz F,et al.2021 ESC/EACTS guidelines for the management of valvular heart disease[J].Eur Heart J,2022,43(7):561-632.DOI:10.1093/eurheartj/ehab395.
- [4]Otto CM,Nishimura RA,Bonow RO,et al.2020 ACC/AHA guideline for the management of patients with valvular heart disease:executive summary:a report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines[J].J Am Coll Cardiol,2021,77(4):450-500.DOI:10.1016/j.jacc.2020.11.035.
- [5]Liu L,Yao X,Peng Y,et al.One-year outcome after transcatheter aortic valve replacement for aortic regurgitation:a single-center study[J].J Card Surg,2022,37(4):882-892.DOI:10.1111/jocs.16238.
- [6]Liu H,Yang Y,Wang W,et al.Transapical transcatheter aortic valve replacement for aortic regurgitation with a secondgeneration heart valve[J].J Thorac Cardiovasc Surg,2018,156(1):106-116.DOI:10.1016/j.jtcvs.2017.12.150.
- [7]国家心血管病专家委员会微创心血管外科专业委员会.中国经导管主动脉瓣置入术(TAVI)多学科专家共识[J].中华胸心血管外科杂志,2018,34(12):705-712.DOI:10.3760/cma.j.issn.1001.4497.2018.12.001
- [8]Guo R,Xie M,Yim WY,et al.Dose approach matter?A meta-analysis of outcomes following transfemoral versus transapical transcatheter aortic valve replacement[J].BMC Cardiovasc Disord,2021,21(1):358.DOI:10.1186/s12872-021-02158-4.
- [9]Kumar N,Khera R,Fonarow GC,et al.Comparison of outcomes of transfemoral versus transapical approach for transcatheter aortic valve implantation[J].Am J Cardiol,2018,122(9):1520-1526.DOI:10.1016/j.amjcard.2018.07.025.
- [10]Li X,Kong M,Jiang D,et al.Comparison 30-day clinical complications between transfemoral versus transapical aortic valve replacement for aortic stenosis:a meta-analysis review[J].J Cardiothorac Surg,2013,8:168.DOI:10.1186/1749-8090-8-168.
- [11]Kaneko T.Vemulapalli S,Kohsaka S,et al.Practice patterns and outcomes of transcatheter aortic valve replacement in the United States and Japan:a report from joint data harmonization initiative of STS/ACC TVT and J-TVT[J].J Am Heart Assoc,2022,11(6):e023848.DOI:10.1161/JAHA.121.023848.
- [12]Chen S,Zheng F,Li M,et al.A study on correlation between preprocedural CT indexes and procedural success rate of transfemoral transcatheter aortic valve replacement with different self-expanding valves(VitaFlow or VenusA-Valve)in patients with pure native aortic regurgitation[J].Ann Transl Med,2022,10(11):643.DOI:10.21037/atm-22-2588.
- [13]Sawaya FJ,Deutsch MA,Seiffert M,et al.Safety and efficacy of transcatheter aortic valve replacement in the treatment of pure aortic regurgitation in native valves and failing surgical bioprostheses:results from an international registry study[J].JACC Cardiovasc Interv,2017,10(10):1048-1056.DOI:10.1016/j.jcin.2017.03.004.
- [14]Zheng HJ,Cheng YB,Yan CJ,et al.Transfemoral transcatheter aortic valve replacement for pure native aortic regurgitation:one-year outcomes of a single-center study[J].BMC Cardiovasc Disord,2023,23(1):330.DOI:10.1186/s12872-023-03329-1.
- [15]Chen Y.Lu ZN,Yao J,et al.A novel anatomic classification to guide transcatheter aortic valve replacement for pure aortic regurgitation[J].Echocardiography,2022,39(12):1571-1580.DOI:10.1111/echo.15490.
- [16]Dai H,Zhou D.Yidilisi A,et al.Self-expanding transcatheter aortic valve replacement for pure aortic regurgitation with extremely horizontal aorta:a case series[J].J Invasive Cardiol,2022,34(3):E257-E258.
- [17]金屏,徐臣年,翟蒙恩,等.股动脉经导管主动脉瓣置换治疗单纯主动脉瓣反流[J].中国体外循环杂志,2022,20(3):160-164.DOI:10.13498/j.cnki.chin.j.ecc.2022.03.07.
- [18]李捷,孙英皓,李光,等.经动脉入路经导管主动脉瓣置换术治疗单纯主动脉瓣反流的初步经验[J].中国介入心脏病学杂志,2021,29(12):678-683.DOI:10.3969/j.issn.1004-8812.2021.12.005.
- [19]程帅,张铮,曹丰,等.经股动脉途径主动脉瓣置入术治疗严重主动脉瓣反流效果观察[J].临床心血管病杂志,2021,37(11):1051-1055.DOI:10.13201/j.issn.1001-1439.2021.11.017.
- [20]Wernly B,Eder S,Navarese EP,et al.Transcatheter aortic valve replacement for pure aortic valve regurgitation:"on-label"versus"off-label"use of TAVR devices[J].Clin Res Cardiol,2019,108(8):921-930.DOI:10.1007/s00392-019-01422-0.
- [21]Huded CP,Allen KB,Chhatriwalla AK.Counterpoint:challenges and limitations of transcatheter aortic valve implantation for aortic regurgitation[J].Heart,2021,107(24):1942-1945.DOI:10.1136/heartjnl-2020-318682.
- [22]Yoon SH,Schmidt T,Bleiziffer S,et al.Transcatheter aortic valve replacement in pure native aortic valve regurgitation[J].J Am Coll Cardiol,2017,70(22):2752-2763.DOI:10.1016/j.jacc.2017.10.006.
- [23]Nkomo VT,Gardin JM,Skelton TN,et al.Burden of valvular heart diseases:a population-based study[J].Lancet,2006,368(9540):1005-1011.DOI:10.1016/S0140-6736(06)69208-8.
- [24]Pan W,Zhou D,Cheng L,et al.Aortic regurgitation is more prevalent than aortic stenosis in Chinese elderly population:implications for transcatheter aortic valve replacement[J].Int J Cardiol,2015,201:547-548.DOI:10.1016/j.ijard.2014.10.069.
- [25]齐喜玲,许海燕,刘庆荣,等.中国老年退行性心脏瓣膜病住院患者诊疗现状分析[J].中国循环杂志,2019,34(8):771-776.DOI:10.3969/j.issn.1000-3614.2019.08.007.
- [26]Hu P,Liu XB,Liang J,et al.A hospital-based survey of patients with severe valvular heart disease in China[J].Int J Cardiol,2017,231:244-247.DOI:10.1016/j.ijcard.2016.11.301.
- [27]lung B,Delgado V,Rosenhek R,et al.Contemporary presentation and management of valvular heart disease:the Eurobservational research programme valvular heart diseaseⅡsurvey[J].Circulation,2019,140(14):1156-1169.DOI:10.1161/CIRCULATIONAHA.119.041080.
- [28]Yin WH,Lee YT,Tsao TP,et al.Outcomes of transcatheter aortic valve replacement for pure native aortic regurgitation with the use of newer-vs.early-generation devices[J].Ann Transl Med,2022,10(1):24.DOI:10.21037/atm-21-6936.
- [29]Delhomme C,Urena M,Zouaghi O,et al.Transcatheter aortic valve implantation using the SAPIEN 3 valve to treat aortic regurgitation:the French multicentre S3AR study[J].Arch Cardiovasc Dis,2023,116(2):98-105.DOI:10.1016/j.acvd.2022.12.003.
- [30]Sanchez-Luna JP,Martin P,Dager AE,et al.Clinical outcomes of TAVI with the Myval balloon-expandable valve for non-calcified aortic regurgitation[J].EuroIntervention,2023,19(7):580-588.DOI:10.4244/EIJ-D-23-00344.
- [31]Oettinger V,Hilgendorf I,Wolf D,et.Treatment of pure aortic regurgitation using surgical or transcatheter aortic valve replacement between 2018 and 2020 in Germany[J].Front Cardiovasc Med,2023,10:1091983.DOI:10.3389/fcvm.2023.1091983.
- [32]Mentias A,Saad M,Menon V,et al.Transcatheter vs.surgical aortic valve replacement in pure native aortic regurgitation[J].Ann Thorac Surg,2023,115(4):870-876.DOI:10.1016/j.athoracsur.2022.09.016.
- [33]Koch R,Inci E,Grubb K,et al.A comparison of thirty-day clinical and echocardiographic outcomes of patients undergoing transcatheter vs.surgical aortic valve replacement for native aortic insufficiency[J].Cardiovasc Revasc Med,2023,46:85-89.DOI:10.1016/j.carrev.2022.08.010.
- [34]Baumbach A,Patel KP,Kennon S,et al.A heart valve dedicated for aortic regurgitation:review of technology and early clinical experience with the transfemoral Trilogy system[J].Catheter Cardiovasc Interv,2023,102(4):766-771.DOI:10.1002/ccd.30795.
- [35]Hensey M,Murdoch DJ,Sathananthan J,et al.First-inhuman experience of a new-generation transfemoral transcatheter aortic valve for the treatment of severe aortic regurgitation:the J-Valve transfemoral system[J].EuroIntervention,2019,14(15):e1553-e1555.DOI:10.4244/EU-D-18-00935.
- [36]Deharo P,Bisson A,Herbert J,et al.Transcatheter valvein-valve aortic valve replacement as an alternative to surgical rereplacement[J].J Am Coll Cardiol,2020,76(5):489-499.DOI:10.1016/j.jacc.2020.06.010.
- [37]Bleiziffer S,Simonato M,Webb JG,et al.Long-term outcomes after transcatheter aortie valve implantation in failed biopro sthetic valves[J].Eur Heart J,2020,41(29):2731-2742.DOI:10.1093/eurheartj/ehaa544.
- [38]Hirji SA,Percy ED,Zogg CK,et al.Comparison of in-hospital outcomes and readmissions for valve-in-valve transcatheter aortic valve replacement vs.reoperative surgical aortic valve replacement:a contemporary assessment of real-world outcomes[J].Eur Heart J,2020,41(29):2747-2755.DOI:10.1093/eurheartj/ehaa252.
- [39]Blanke P,Weir-McCall JR,Achenbach S,et al.Computed tomography imaging in the context of transcatheter aortic yalve implantation(TAVI)/transcatheter aortic valve replacement(TAVR):an expert consensus document of the society of cardiovascular computed tomography[J].JACC Cardiovasc Imaging,2019,12(1):1-24.DOI:10.1016/j.jcmg.2018.12.003.
- [40]潘文志,龙愉良,周达新,等,单纯主动脉瓣反流经导管主动脉瓣置换的解剖分析及操作技巧[J].中华心脏与心律电子杂志,2023,11(3):141-146.DOI:10.3877/cma.j.issn.2095-6568.2023.03.002.
- [41]Gao X,Zhang J,Kong X,et al.Transcatheter aortic valve replacement in patients with pure native aortic regurgitation:results from a multicenter registry study[J].Cardiol Discov,2023.DOI:10.1097/CD9.0000000000000101.
- [42]Nishimura RA,O'Gara PT,Bavaria JE,et al.2019 AATS/ACC/ASE/SCAI/STS expert consensus systems of care document:a proposal to optimize care for patients with varvular heart disease:a joint report of the American Association for Thoracie Surgery,American College of Cardiology,American Society of Echocardiography,Society for Cardiovascular Angiography and Interventions,and Society of Thoracic Surgeons[J].J Am Coll Cardiol,2019,73(20):2609-2635.DOI:10.1016/j.jacc.2018.10.007.
- [43]中国医师协会心血管内科医师分会结构性心脏病专业委员会,中华医学会心血管病学分会结构性心脏病学组.经导管主动脉瓣置换术团队建设及运行规范中国专家建议[J].中国介入心脏病学杂,2018,26(1):2-6.DOI:10.3969/j.issn.1004-8812.2018.01.002.
- [44]Malaisrie SC,Szeto WY,Halas M,et al.2021 The American Association for Thoracic Surgery expert consensus document:Surgical treatment of acute type A aortic dissection[J].J Thorac cardiovasc Surg,2021,162(3):735-758.DOI:10.1016/j.jtcvs.2021.04.053.
- [45]Lv WY,Zhao ZG,Li SJ,et al.Progression of the ascending artic diameter after transcatheter aortic valve implantation:based on computed tomography images[J].J Invasive Cardiol,2019,31(8):E234-E241.
- [46]侯士强,陈莎莎,龙渝良,等.经导管主动脉瓣置换术治疗二叶式主动脉瓣狭窄的术中投照角度预测值分析[J].中国介入心脏病学杂志,2021,29(2):68-74.DOI:10.3969/j.issn.1004-8812.2021.02.003.
- [47]Genereux P,Piazza N,Alu MC,et al.Valve Academic Research Consortium 3:updated endpoint definitions for aortic valve clinical research[J].J Am Coll Cardiol,2021,77(21):2717-2746.DOI:10.1016/j.jacc.2021.02.038.
- [48]Chen SS,Lin DW,Qi YM,et al.A transcatheter"sandwich"valve-in-valve implantation for pure aortic regurgitation:a report of 2 cases[J].Cardiology Plus,2023,8(3):211-215.DOI:10.1097/CP9.000000000000005 9.
- [49]Pibarot P,Hahn RT,Weissman NJ,et al.Assessment of paravalvular regurgitation following TAVR:a proposal of unifying grading scheme[J].JACC Cardiovasc Imaging,2015,8(3):340-360.DOI:10,1016/j.jcmg.2015.01.008.
- [50]Siontis GC,Jüni P,Pilgrim T,et al.Predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVR:a Meta-analysis[J].J Am Coll Cardiol,2014,64(2):129-140.DOI:10.1016/j.jacc.2014.04.033.
- [51]Ten Berg J,Sibbing D,Rocca B,et al.Management of antithrombotic therapy in patients undergoing transcatheter aortic valve implantation:a consensus document of the ESC Working Group on Thrombosis and the European Association of Percutaneous Cardiovascular Interventions(EAPCI),in collaboration with the ESC Council on Valvular Heart Disease[J].Eur Heart J,2021,42(23):2265-2269.DOI:10.1093/eurheartj/ehab196.
- [52]Zhang MK,Li LN,Xue H,et al.Left ventricle reverse remodeling in chronic aortic regurgitation patients with dilated ventricle after aortic valve replacement[J].J Cardiothorac Surg,2022,17(1):8.DOI:10.1186/s13019-022-01754-5.
- [531 Amano M,Izumi C,Imamura S,et al.Late recurrence of left ventricular dysfunction after aortic valve replacement for severe chronic aortic regurgitation[J].Int J Cardiol,2016,224:240-244.DOI:10.1016/j.ijcard.2016.09.032.
- [54]赵星,姜兆磊,梅举,等.经导管主动脉瓣置换术对主动脉瓣反流患者术后左心室逆重构影响的临床研究[J].中国胸心血管外科临床杂志,2023,30(8):1121-1127.
- [55]Niu HX,Liu X,Gu M,et sl.Conduction system pacing for post transcatheter aortic valve replacement patients:comparison with right ventricular pacing[J].Front Cardiovasc Med,2021,8:772548.DOI:10.3389/fcvm.2021.772548.
- [56]Vijayaraman P,Canoó,Koruth JS,et al.His-purkinje conduction system pacing following transcatheter aortic valve replacement:feasibility and safety[J].JACC Clin Electrophysiol,2020,6(6):649-657.DOI:10.1016/j.jacep.2020.02.010.
- [57]Kalsi MS,Dayawansa N,Mutha V.Cardiac resynchronisation therapy for reversal of new-onset left bundle branch block and heart failure after surgical aortic valve replacement[J].BMJ Case Rep,2020,13(12):e238130.DOI:10.1136/bcr-2020-238130.