心包腔内注入凝血酶治疗经皮冠状动脉介入治疗围术期急性心脏压塞的疗效和体会(附13例)Intra-pericardial thrombin injection for acute cardiac tamponade during percutaneous coronary intervention
李国庆,穆叶赛·尼加提,雷建新,戴晓燕,王钊,阿木提·司马义,阿德,余小林,郭自同,王保风,谢芳
摘要(Abstract):
目的探讨冠心病经皮冠状动脉介入治疗(PCI)并发冠状动脉穿孔致急性心脏压塞的临床特征、处理方法,以提高抢救成功率。方法回顾性分析2005年1月至2015年12月在新疆维吾尔自治区人民医院心内科住院行PCI时并发冠状动脉穿孔导致急性心脏压塞的冠心病患者13例,分析发生原因、临床表现、处理方法及预后。结果所有患者均得到及时诊断,心包穿刺均获得成功,心包腔内注入凝血酶冻干粉500~1000 U得到有效止血,术后2 h、4 h、6 h、24 h及出院前复查心脏超声未发现新的心包积液及心包粘连。所有患者出院后6个月随访心脏超声未见心包缩窄或粘连。结论急性心脏压塞是PCI术中严重的并发症之一,一旦诊断明确,需紧急心包穿刺引流。心包腔内注入凝血酶能成功止血,提高抢救成功率。
关键词(KeyWords): 经皮冠状动脉介入治疗;冠状动脉穿孔;心脏压塞;凝血酶
基金项目(Foundation):
作者(Author): 李国庆,穆叶赛·尼加提,雷建新,戴晓燕,王钊,阿木提·司马义,阿德,余小林,郭自同,王保风,谢芳
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