药物洗脱支架术后再狭窄八例Observation of 8 patients with restenosis after drug-eluting stents implantation
胡健,沈卫峰,张建盛,张瑞岩,张奇,杨震坤
摘要(Abstract):
目的分析药物洗脱支架术后再狭窄的因素。方法2002年9月至2004年5月,8例经冠状动脉造影证实有药物洗脱支架术后再狭窄的患者入选本研究。所有患者均行血管内超声(IVUS)检查。再狭窄分为支架内再狭窄和节段内再狭窄。支架内再狭窄定义为支架内径狭窄大于50%;节段内再狭窄定义为支架近、远段5mm内血管内径狭窄大于50%。结果8例再狭窄患者中,5例是支架近段再狭窄,3例支架内再狭窄(其中2例是由于支架未充分扩张所致)。支架置入过程中,5例曾行支架外后扩张,1例未完全覆盖病变。IVUS显示,8例均为局灶性狭窄,无一例弥漫性再狭窄。结论药物洗脱支架术后再狭窄主要与支架外血管损伤及未完全覆盖病变有关,且再狭窄主要发生在支架近段。即使发生支架内再狭窄,病变也较局限。
关键词(KeyWords): 药用制剂;支架;冠状动脉再狭窄;超声检查,介入性
基金项目(Foundation):
作者(Author): 胡健,沈卫峰,张建盛,张瑞岩,张奇,杨震坤
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