不同药物和剂量静脉溶栓治疗急性心肌梗塞92例初步观察A Primary observation of therapy with thrombolitic agents of different agents and doses for myocardiol infarction in cases
丁文惠,胡大一,张钧华,冯大力,邵耕,朱国英,霍勇,瞿新梅,汪丽蕙
摘要(Abstract):
采用日本绿十字尿激酶(UK);美国,德国链激酶(SK)静滴治疗急性心肌梗塞92例.根据临床指标判定血管再通率分别为UK96万IU组50.0%(17/34),UK150万IU组61.9%(13/21),SK150万IU组64.8%(24/37).UK剂量加大,出血未增加,SK的轻度出血、过敏、低血压略高于Uk,但均不严重,容易处理.
关键词(KeyWords): 血栓溶解疗法;尿激酶;链激酶;心肌梗塞
基金项目(Foundation):
作者(Author): 丁文惠,胡大一,张钧华,冯大力,邵耕,朱国英,霍勇,瞿新梅,汪丽蕙
参考文献(References):
- [1] 徐义枢,等.静脉溶栓治疗急性心肌梗塞.中国循环杂志,1986,1:145.
- [2] 陈春亮,等.中等剂量尿激酶对急性心肌梗塞的溶栓效果.中华内科杂志,1989,28:278.
- [3] 胡大一等,溶栓治疗急性心肌梗塞40例初步报告.中华心血管病杂志,1991. 19:143.
- [4] Wall,TC.,et al.Results of high dose intravenous Urokinase for acute myocardial infarction.Am J cardiol,1990,65:124.
- [5] Mathey.DG.,et al.Intravenous Urokinase in acute myocardial infarction.Am J cardiol,1985,55,878.
- [6] 冠心病和瓣膜疾病介入性治疗及溶栓疗法专题研讨会纪要 附件:急性心肌梗塞溶栓疗法参考方案.中华心血管病杂志,1991,19:137.
- [7] Gottlich,CM.,et al.Do different doses of intravenous Streptokinase alter the frequency of coronary reperfusion in acute myocardial infarction.Am J cardiol,1988. 62:843.
- [8] Tennant,SN.,et al.Intracoronary thrombolysis in patients with acute myocardiol infarction comparison of the efficacy of Urokinase with Streptokinase.Circulation,1984. 69:756.
- [9] Lew.A.,et al.The effects of the rate of intravenous infusion of Streptokinase and the duration of symptoms on the time interval to reperfusion in patients with acute myocardial infarction.Thrombolysis.1985. 72:1052.
- [10] ISIS-2 collaborative group.Randomized trial of intravenous streptokinase.oral aspirin,both.or neither among 17187 cases of suspected acute myocardial infarction.Lancet,1988,2:349.