吴义林,骆峰,施鸿毓,仇兴标,曲新凯,韩文正,戴锦杰,关韶峰,侯旭敏,叶颖,薛玉增,陈晖,方唯一

• 1:上海交通大学附属胸科医院心血管内科
• 2:山东省聊城市人民医院心血管内科

摘要(Abstract)：

目的对比研究直接旋磨及补救旋磨治疗重度冠状动脉钙化病变的安全性及有效性。方法回顾性分析自2012年5月至2015年7月在上海市胸科医院及聊城市人民医院行冠状动脉旋磨术联合药物洗脱支架置入术58例患者,包括直接旋磨组27例、补救旋磨组31例。比较两组患者术前一般临床资料、病变及手术特征,术中并发症,住院期间及1年随访期主要不良心脑血管事件(main adverse cardiac and cerebrovascular events,MACCE)发生情况。结果两组患者一般基线资料比较,差异均无统计学意义(均P>0.05);但直接旋磨组患者既往PCI比例显著大于补救旋磨组(33.3%比12.9%,P=0.039),差异有统计学意义。两组患者病变特点及手术特征比较,差异均无统计学意义(均P>0.05);但直接旋磨组球囊使用数[2(1,2)枚比3(1,5)枚,P<0.001]、术后肌钙蛋白峰值[0.5(0.1,2.3)μg/L比1.1(0.3,3.0)μg/L,P=0.032]均小于补救旋磨组,差异均有统计学意义。两组患者PCI成功率、术中并发症发生率、死亡率、住院期间MACCE发生率比较,差异均无统计学意义(均P>0.05);1年随访期MACCE发生率比较,差异亦无统计学意义(P>0.05)。结论本研究表明在接受旋磨术联合药物洗脱支架置入术的重度冠状动脉钙化病变患者中,补救旋磨与直接旋磨的安全性及有效性相当。

关键词(KeyWords)： 冠心病;钙化病变;旋磨术;药物洗脱支架

Abstract:

Keywords:

基金项目(Foundation): 上海市胸科医院科技发展基金(2014YZDH20201)

作者(Author): 吴义林,骆峰,施鸿毓,仇兴标,曲新凯,韩文正,戴锦杰,关韶峰,侯旭敏,叶颖,薛玉增,陈晖,方唯一

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